Back to Search
Start Over
Validation of a method to monitor the occurrence of 20 relevant pharmaceuticals and personal care products in 167 bottled waters
- Source :
- Science of the Total Environment, Science of the Total Environment, Elsevier, 2017, 587-588, pp.118-127. ⟨10.1016/j.scitotenv.2017.02.074⟩
- Publication Year :
- 2016
-
Abstract
- International audience; Research on emerging substances in drinking water presents major interest and the possibility of trace contamination has seen increasing concern from the scientific community and the public authorities. More particularly, residues of pharmaceuticals and personal care products (PPCPs) in bottled water are a very important issue due to societal concerns and potential media impact. In this context, it has become necessary to carry out reliable monitoring. This requires measurements of high quality with demonstration of accuracy and well-defined uncertainty. In this study, 20 pharmaceutical compounds were targeted for the first time in 167 bottled waters from France and other European countries. An isotope dilution-solid phase extraction-liquid chromatography mass spectrometry method, together with stringent quality control and quality assurance protocols, was developed and validated according to French mandatory standards. Recoveries between 87% and 112% were obtained with coefficient of variation below 20%. Operational limits of quantification (LOQ) were comprised between 5 and 30 ng L− 1. Expanded uncertainties (k = 2) ranged between 16% and 43% and were below 35% for half of the compounds. The survey showed only four positive quantifications, thereby highlighting the rarity of contamination.
- Subjects :
- Engineering
Environmental Engineering
media_common.quotation_subject
MESH: Pharmaceutical Preparations
Context (language use)
QA/QC
Cosmetics
010501 environmental sciences
Quality of measurements
01 natural sciences
Environmental impact of pharmaceuticals and personal care products
Tandem Mass Spectrometry
Environmental health
Environmental monitoring
Environmental Chemistry
MESH: Chromatography, High Pressure Liquid
Waste Management and Disposal
Chromatography, High Pressure Liquid
0105 earth and related environmental sciences
media_common
Bottled waters
business.industry
[CHIM.ORGA]Chemical Sciences/Organic chemistry
Drinking Water
010401 analytical chemistry
Solid Phase Extraction
Contamination
Bottled water
MESH: Cosmetics
Pollution
6. Clean water
3. Good health
0104 chemical sciences
Europe
Pharmaceutical Preparations
Personal care products
Pharmaceuticals
business
Quality assurance
MESH: Environmental Monitoring
Water Pollutants, Chemical
Chromatography, Liquid
Environmental Monitoring
Subjects
Details
- ISSN :
- 18791026 and 00489697
- Database :
- OpenAIRE
- Journal :
- The Science of the total environment
- Accession number :
- edsair.doi.dedup.....2c882e148baa04227c23de35edc8daa0