Back to Search
Start Over
Transcranial optical monitoring of cerebrovascular hemodynamics in acute stroke patients
- Source :
- Optics Express. 17:3884
- Publication Year :
- 2009
- Publisher :
- The Optical Society, 2009.
-
Abstract
- "Diffuse correlation spectroscopy" (DCS) is a technology for non-invasive transcranial measurement of cerebral blood flow (CBF) that can be hybridized with "near-infrared spectroscopy" (NIRS). Taken together these methods hold potential for monitoring hemodynamics in stroke patients. We explore the utility of DCS and NIRS to measure effects of head-of-bed (HOB) positioning at 30 degrees , 15 degrees , 0 degrees , -5 degrees and 0 degrees angles in patients with acute ischemic stroke affecting frontal cortex and in controls. HOB positioning significantly altered CBF, oxy-hemoglobin (HbO(2)) and total-hemoglobin (THC) concentrations. Moreover, the presence of an ipsilateral infarct was a significant effect for all parameters. Results are consistent with the notion of impaired CBF autoregulation in the infarcted hemisphere.
- Subjects :
- Adult
Male
medicine.medical_specialty
Optical Phenomena
Point-of-Care Systems
Posture
Diagnostic Techniques, Neurological
Hemodynamics
Single-photon emission computed tomography
Article
Functional Laterality
Hemoglobins
Optics
Internal medicine
medicine
Homeostasis
Humans
Stroke
Aged
Acute stroke
Aged, 80 and over
Spectroscopy, Near-Infrared
medicine.diagnostic_test
business.industry
Cerebral infarction
Cerebral Infarction
Middle Aged
Laser Doppler velocimetry
medicine.disease
Atomic and Molecular Physics, and Optics
Cerebral blood flow
Positron emission tomography
Case-Control Studies
Cerebrovascular Circulation
Oxyhemoglobins
Cardiology
Female
business
Subjects
Details
- ISSN :
- 10944087
- Volume :
- 17
- Database :
- OpenAIRE
- Journal :
- Optics Express
- Accession number :
- edsair.doi.dedup.....2d41def8e0ea2ff05b98400d8e955993