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Antioxidant, anticancer, apoptosis properties and chemical composition of black truffle Terfezia claveryi

Authors :
Aman Shah Abdul Majid
Saad S. Dahham
Amin Malik Shah Abdul Majid
Ahmad H. Ibrahim
Sawsan S. Al-Rawi
Source :
Saudi Journal of Biological Sciences, Vol 25, Iss 8, Pp 1524-1534 (2018)

Abstract

Desert truffles are seasonal and important edible fungi that grow wild in many countries around the world. Truffles are natural food sources that have significant compositions. In this work, the antioxidant, chemical composition, anticancer, and antiangiogenesis properties of the Terfezia claveryi truffle were investigated. Solvent extractions of the T. claveryi were evaluated for antioxidant activities using (DPPH, FRAP and ABTS methods). The extracts cytotoxicity on the cancer cell lines (HT29, MCF-7, PC3 and U-87 MG) was determined by MTT assay, while the anti-angiogenic efficacy was tested using ex-vivo assay. All extracts showed moderate anticancer activities against all cancer cells (p

Details

Language :
English
ISSN :
1319562X
Database :
OpenAIRE
Journal :
Saudi Journal of Biological Sciences
Accession number :
edsair.doi.dedup.....2da84dc0893e9fd9b1c178f47ce7cde0
Full Text :
https://doi.org/10.1016/j.sjbs.2016.01.031