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Antioxidant, anticancer, apoptosis properties and chemical composition of black truffle Terfezia claveryi
- Source :
- Saudi Journal of Biological Sciences, Vol 25, Iss 8, Pp 1524-1534 (2018)
-
Abstract
- Desert truffles are seasonal and important edible fungi that grow wild in many countries around the world. Truffles are natural food sources that have significant compositions. In this work, the antioxidant, chemical composition, anticancer, and antiangiogenesis properties of the Terfezia claveryi truffle were investigated. Solvent extractions of the T. claveryi were evaluated for antioxidant activities using (DPPH, FRAP and ABTS methods). The extracts cytotoxicity on the cancer cell lines (HT29, MCF-7, PC3 and U-87 MG) was determined by MTT assay, while the anti-angiogenic efficacy was tested using ex-vivo assay. All extracts showed moderate anticancer activities against all cancer cells (p
- Subjects :
- Antioxidant
DPPH
Black truffle
medicine.medical_treatment
Ethyl acetate
Biology
03 medical and health sciences
chemistry.chemical_compound
Squalene
0404 agricultural biotechnology
0302 clinical medicine
T. claveryi
medicine
MTT assay
Food science
lcsh:QH301-705.5
Lupeol
Cancer
ABTS
Stigmasterol
Agricultural and Biological Sciences(all)
04 agricultural and veterinary sciences
040401 food science
lcsh:Biology (General)
chemistry
Biochemistry
030220 oncology & carcinogenesis
Angiogenesis
General Agricultural and Biological Sciences
Subjects
Details
- Language :
- English
- ISSN :
- 1319562X
- Database :
- OpenAIRE
- Journal :
- Saudi Journal of Biological Sciences
- Accession number :
- edsair.doi.dedup.....2da84dc0893e9fd9b1c178f47ce7cde0
- Full Text :
- https://doi.org/10.1016/j.sjbs.2016.01.031