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Delta-neutrophil index: a potential predictor of coronary artery involvement in Kawasaki disease by retrospective analysis
- Source :
- Rheumatology International. 39:1955-1960
- Publication Year :
- 2019
- Publisher :
- Springer Science and Business Media LLC, 2019.
-
Abstract
- DNI is the immature granulocyte fraction provided by a blood cell analyzer, which is determined by subtracting the fraction of mature polymorphonuclear leukocytes from the sum of myeloperoxidase-reactive cells. We aimed to evaluate the role of Delta-neutrophil index (DNI) in cardiac prognosis prediction in children with Kawasaki disease (KD). Medical records of 193 patients were retrospectively reviewed. The values of DNI, white blood cells, erythrocyte sedimentation rate, the percent of polymorphonuclear leucocytes, C-reactive protein, aspartate transaminase, alanine aminotransferase, total bilirubin data of children with KD were analyzed. Also, sex and age of children were compared. The value of DNI was higher in children with cardiac complications [median 0.8 (0–0.26) vs 5.3 (3.55–8.95); P
- Subjects :
- Male
medicine.medical_specialty
Neutrophils
Immunology
Aspartate transaminase
Blood Sedimentation
Coronary Artery Disease
Mucocutaneous Lymph Node Syndrome
Severity of Illness Index
Gastroenterology
Leukocyte Count
03 medical and health sciences
0302 clinical medicine
Rheumatology
Internal medicine
medicine
Humans
Immunology and Allergy
030212 general & internal medicine
Child
Retrospective Studies
030203 arthritis & rheumatology
medicine.diagnostic_test
Receiver operating characteristic
biology
business.industry
Immature Granulocyte
Infant
Complete blood count
Prognosis
medicine.disease
Confidence interval
medicine.anatomical_structure
Child, Preschool
Erythrocyte sedimentation rate
biology.protein
Female
Kawasaki disease
business
Biomarkers
Artery
Subjects
Details
- ISSN :
- 1437160X and 01728172
- Volume :
- 39
- Database :
- OpenAIRE
- Journal :
- Rheumatology International
- Accession number :
- edsair.doi.dedup.....2db96ab7f678735e453c939a26dcfb4e
- Full Text :
- https://doi.org/10.1007/s00296-019-04448-9