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Delta-neutrophil index: a potential predictor of coronary artery involvement in Kawasaki disease by retrospective analysis

Authors :
Jong Wook Lee
Kyung Ok Ko
Sang Hun Lee
Jung Min Yoon
Eun Jung Cheon
Jae Woo Lim
Young Hwa Song
Source :
Rheumatology International. 39:1955-1960
Publication Year :
2019
Publisher :
Springer Science and Business Media LLC, 2019.

Abstract

DNI is the immature granulocyte fraction provided by a blood cell analyzer, which is determined by subtracting the fraction of mature polymorphonuclear leukocytes from the sum of myeloperoxidase-reactive cells. We aimed to evaluate the role of Delta-neutrophil index (DNI) in cardiac prognosis prediction in children with Kawasaki disease (KD). Medical records of 193 patients were retrospectively reviewed. The values of DNI, white blood cells, erythrocyte sedimentation rate, the percent of polymorphonuclear leucocytes, C-reactive protein, aspartate transaminase, alanine aminotransferase, total bilirubin data of children with KD were analyzed. Also, sex and age of children were compared. The value of DNI was higher in children with cardiac complications [median 0.8 (0–0.26) vs 5.3 (3.55–8.95); P

Details

ISSN :
1437160X and 01728172
Volume :
39
Database :
OpenAIRE
Journal :
Rheumatology International
Accession number :
edsair.doi.dedup.....2db96ab7f678735e453c939a26dcfb4e
Full Text :
https://doi.org/10.1007/s00296-019-04448-9