Comparative study of the in vitro effect of nanoliposomes with oxidized dextrans on peritoneal cells

Authors :: M. V. Zaikovskaja
T. N. Bistrova
D. A. Iljin
E. G. Ufimceva
E. S. Akhramenko
N. G. Luzgina
A. V. Troitsky
S. A. Arkhipov
V. A. Shkurupiy
E. P. Gulyaeva
Source :: Bulletin of experimental biology and medicine. 146(6)
Publication Year :: 2009
Abstract: We studied the in vitro effect of hybrid molecular-nanosomal biocompatible compositions on cultured peritoneal cells. The compositions consisted of oxidized dextrans with a mean molecular weight of 35 and 60 kDa, which were obtained by chemical and radiochemical oxidation of dextran. Hybrid nanoliposomal compositions of chemically oxidized dextran (permanganate method) had greater biocompatibility and tropic activity to macrophages compared to nanoliposomes of radiochemically oxidized dextran.

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