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The insulo-opercular cortex encodes food-specific content under controlled and naturalistic conditions
- Source :
- Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021), Nature Communications
- Publication Year :
- 2021
- Publisher :
- Nature Portfolio, 2021.
-
Abstract
- The insulo-opercular network functions critically not only in encoding taste, but also in guiding behavior based on anticipated food availability. However, there remains no direct measurement of insulo-opercular activity when humans anticipate taste. Here, we collect direct, intracranial recordings during a food task that elicits anticipatory and consummatory taste responses, and during ad libitum consumption of meals. While cue-specific high-frequency broadband (70–170 Hz) activity predominant in the left posterior insula is selective for taste-neutral cues, sparse cue-specific regions in the anterior insula are selective for palatable cues. Latency analysis reveals this insular activity is preceded by non-discriminatory activity in the frontal operculum. During ad libitum meal consumption, time-locked high-frequency broadband activity at the time of food intake discriminates food types and is associated with cue-specific activity during the task. These findings reveal spatiotemporally-specific activity in the human insulo-opercular cortex that underlies anticipatory evaluation of food across both controlled and naturalistic settings.<br />Animal studies have shown that insulo-opercular network function is critical in gustation and in behaviour based on anticipated food availability. The authors describe activities within the human insulo-opercular cortex which underlie anticipatory food evaluation in both controlled and naturalistic settings.
- Subjects :
- Adult
Male
0301 basic medicine
Food intake
Taste
Science
General Physics and Astronomy
Frontal operculum
Biology
Cognitive neuroscience
Neural circuits
Article
General Biochemistry, Genetics and Molecular Biology
Young Adult
03 medical and health sciences
0302 clinical medicine
Cortex (anatomy)
medicine
Humans
Food evaluation
Cerebral Cortex
Meal
Gustatory system
Multidisciplinary
digestive, oral, and skin physiology
Taste Perception
Electroencephalography
General Chemistry
Middle Aged
Electrophysiological Phenomena
Frontal Lobe
030104 developmental biology
medicine.anatomical_structure
Food
Feeding behaviour
Female
Cues
Insula
Neuroscience
030217 neurology & neurosurgery
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 12
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Nature Communications
- Accession number :
- edsair.doi.dedup.....2e2608d9699fcdfdfa9eff722b368b5c