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Mitral valve prolapse with ventricular arrhythmias: does it carries a worse prognosis?
- Source :
- European Heart Journal Supplements : Journal of the European Society of Cardiology
- Publication Year :
- 2021
- Publisher :
- Oxford University Press (OUP), 2021.
-
Abstract
- The association of mitral valve prolapse (MVP) with ventricular arrhythmias has long been known and has generally been considered a benign condition. In recent years, however, a small but not negligible risk of malignant ventricular arrhythmias and sudden cardiac death has been documented in the large population of subjects with MVP. The main predictors of major arrhythmic risk identified so far include history of syncope, ventricular repolarization abnormalities in the inferior-lateral electrocardiogram leads, right bundle branch block morphology of ventricular ectopic beats, finding of areas of myocardial fibrosis on cardiac magnetic resonance, and mitral annular disjunction (MAD) on echocardiogram, as well as a possible pro-arrhythmic genetic substrate. The stratification of arrhythmic risk, with the active search for red flags and in particular of MAD, is important to identify patients with the malignant arrhythmic variant of MVP in whom to implement closer surveillance and possible therapeutic interventions.
- Subjects :
- Benign condition
Ventricular Repolarization
medicine.medical_specialty
Sudden death
business.industry
Mitral annular disjunction
Large population
Articles
Right bundle branch block
medicine.disease
Sudden cardiac death
Ventricular arrhythmias
Internal medicine
cardiovascular system
medicine
Cardiology
Mitral valve prolapse
AcademicSubjects/MED00200
Ventricular Ectopic Beats
cardiovascular diseases
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 15542815 and 1520765X
- Volume :
- 23
- Database :
- OpenAIRE
- Journal :
- European Heart Journal Supplements
- Accession number :
- edsair.doi.dedup.....2eac33a87dfb0f58d4dc94dcf3f16b13