Back to Search Start Over

Analysing different exposures identifies that wearing masks and establishing COVID-19 areas reduce secondary-attack risk in aged-care facilities

Authors :
Mircea T. Sofonea
Hubert Blain
Amandine Pisoni
Samuel Alizon
Christian Selinger
Bastien Reyné
Stéphanie Miot
Edouard Tuaillon
Jean Bousquet
Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC)
Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])
Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)
Pathogenesis and Control of Chronic and Emerging Infections (PCCEI)
Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Université des Antilles (UA)-Etablissement français du don du sang [Montpellier]
Charité - UniversitätsMedizin = Charité - University Hospital [Berlin]
Humboldt University Of Berlin
Berlin Institute of Health (BIH)
Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc-Roussillon (MACVIA-LR)
Université Montpellier 1 (UM1)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Universitaire de Nîmes (CHU Nîmes)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-European Innovation Partnership on Active and Healthy Ageing Reference Site (EIP on AHA)
Commission Européenne-Commission Européenne-Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO)
EuroMov - Digital Health in Motion (Euromov DHM)
IMT - MINES ALES (IMT - MINES ALES)
Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Université de Montpellier (UM)
Centre interdisciplinaire de recherche en biologie (CIRB)
Labex MemoLife
École normale supérieure - Paris (ENS-PSL)
Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Collège de France (CdF (institution))-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris)
Université Paris sciences et lettres (PSL)-École normale supérieure - Paris (ENS-PSL)
Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
ANR-20-COVI-0098,PHYEPI,Intégration de données de séquences et d'incidence pour analyser et contrôler les épidémies virales(2020)
Génétique et évolution des maladies infectieuses (GEMI)
Alizon, Samuel
Source :
International Journal of Epidemiology, International Journal of Epidemiology, 2021, 50 (6), pp.1788-1794. ⟨10.1093/ije/dyab121⟩, International Journal of Epidemiology, Oxford University Press (OUP), 2021, ⟨10.1093/ije/dyab121⟩, Int J Epidemiol
Publication Year :
2021
Publisher :
Oxford University Press, 2021.

Abstract

Background The COVID-19 epidemic has spread rapidly within aged-care facilities (ACFs), where the infection-fatality ratio is high. It is therefore urgent to evaluate the efficiency of infection prevention and control (IPC) measures in reducing SARS-CoV-2 transmission. Methods We analysed the COVID-19 outbreaks that took place between March and May 2020 in 12 ACFs using reverse transcription–polymerase chain reaction (RT–PCR) and serological tests for SARS-CoV-2 infection. Using maximum-likelihood approaches and generalized linear mixed models, we analysed the proportion of infected residents in ACFs and identified covariates associated with the proportion of infected residents. Results The secondary-attack risk was estimated at 4.1%, suggesting a high efficiency of the IPC measures implemented in the region. Mask wearing and the establishment of COVID-19 zones for infected residents were the two main covariates associated with lower secondary-attack risks. Conclusions Wearing masks and isolating potentially infected residents appear to be associated with a more limited spread of SARS-CoV-2 in ACFs.

Subjects

Subjects :
Epidemiology
Generalised Linear Mixed Models
[SDV.BID.SPT]Life Sciences [q-bio]/Biodiversity/Systematics, Phylogenetics and taxonomy
Corrections
law.invention
0302 clinical medicine
law
[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases
Medicine
Infection control
aged care facilities
secondary-attack risk
030212 general & internal medicine
aged-care facilities
[SDV.MHEP.ME] Life Sciences [q-bio]/Human health and pathology/Emerging diseases
Likelihood Functions
[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases
[SDV.MHEP.GEG] Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontology
[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]
secondary attack risk
[SDV.MHEP.GEG]Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontology
Masks
General Medicine
[SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM]
3. Good health
Transmission (mechanics)
[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology
[SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases
Original Article
2019-20 coronavirus outbreak
Coronavirus disease 2019 (COVID-19)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
03 medical and health sciences
[SDV.EE.ECO]Life Sciences [q-bio]/Ecology, environment/Ecosystems
Environmental health
Humans
AcademicSubjects/MED00860
Aged care
Epidemics
mask wearing
Aged
[SDV.EE.SANT]Life Sciences [q-bio]/Ecology, environment/Health
[SDV.GEN.GPO]Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE]
SARS-CoV-2
business.industry
Outbreak
COVID-19
[INFO.INFO-MO]Computer Science [cs]/Modeling and Simulation
generalized linear mixed models
[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
[SDE.BE]Environmental Sciences/Biodiversity and Ecology
business
030217 neurology & neurosurgery
[SDV.EE.IEO]Life Sciences [q-bio]/Ecology, environment/Symbiosis

Details

Language :
English
ISSN :
14643685 and 03005771
Database :
OpenAIRE
Journal :
International Journal of Epidemiology
Accession number :
edsair.doi.dedup.....2ee3479618613dfe0f3ba683378772a0