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Is Systematic Sextant Biopsy Suitable for the Detection of Clinically Significant Prostate Cancer?
- Source :
- Urol Int 2000;65:80–83, ISSN: 0042-1138
- Publication Year :
- 2000
- Publisher :
- S. Karger AG, 2000.
-
Abstract
- Background: The optimal extent of the prostate biopsy remains controversial. There is a need to avoid detection of insignificant cancer but not to miss significant and curable tumors. In alternative treatments of prostate cancer, repeated sextant biopsies are used to estimate the response. The aim of this study was to investigate the reliability of a repeated systematic sextant biopsy as the standard biopsy technique in patients with significant tumors which are being considered for curative treatment. Methods: Systematic sextant biopsy was performed in vitro in 92 radical prostatectomy specimens. Of these patients, 81 (88.0%) had palpable lesions. Results: Of the 92 investigated patients, 70 (76.1%) had potentially curable pT2-3pN0 prostate cancers. In these patients, the cancer was detected only in 72.9% of cases by a repeated in vitro biopsy. In the pT2 tumors, there was a detection rate of only 66.7%. Conclusions: This study underlines the fact that a considerable number of significant and potentially curable tumors remain undetected by the conventional sextant biopsy. A negative sextant biopsy does not rule out significant prostate cancer. Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
- Subjects :
- Male
medicine.medical_specialty
Prostate biopsy
Urology
Prostate cancer
Prostate
Tumor stage
Biopsy
Insignificant cancer
medicine
Humans
Prostate disease
ddc:610
Aged
medicine.diagnostic_test
business.industry
Biopsy, Needle
Prostatic Neoplasms
Reproducibility of Results
Middle Aged
Sextant, Biopsie, Prostatakrebs, Stadienbestimmung, Onkologie, radikale Prostatektomie
Systematic sextant biopsy, Prostate cancer, Tumor stage, Radical prostatectomy
medicine.disease
Surgery
medicine.anatomical_structure
Sextant biopsy
Radiology
business
Subjects
Details
- ISSN :
- 14230399 and 00421138
- Volume :
- 65
- Database :
- OpenAIRE
- Journal :
- Urologia Internationalis
- Accession number :
- edsair.doi.dedup.....2ee622b9962412b66c574090d3c64197