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Switching to Rac and Rho
- Source :
- Structure. 3(12):1281-1284
- Publication Year :
- 1995
- Publisher :
- Elsevier BV, 1995.
-
Abstract
- Could the recent elucidation of the structure of the Rap–Raf complex have been the first glimpse of a universal arrangement between GTPase switches and kinase cascades, as a number of recent reports show that Ras is not unique in its ability to start a signalling ‘chain reaction'?
- Subjects :
- Mitogen-Activated Protein Kinase Kinases
Kinase
GTPase-Activating Proteins
GTPase
Protein Serine-Threonine Kinases
Biology
MAP Kinase Kinase Kinases
GTP Phosphohydrolases
Cell biology
Proto-Oncogene Proteins c-raf
Proto-Oncogene Proteins p21(ras)
rap GTP-Binding Proteins
Signalling
GTP-Binding Proteins
Structural Biology
Multigene Family
Proto-Oncogene Proteins
Calcium-Calmodulin-Dependent Protein Kinases
Animals
Humans
Phosphorylation
Protein Kinases
Protein Processing, Post-Translational
Molecular Biology
Signal Transduction
Subjects
Details
- ISSN :
- 09692126
- Volume :
- 3
- Issue :
- 12
- Database :
- OpenAIRE
- Journal :
- Structure
- Accession number :
- edsair.doi.dedup.....2fa7350577a06201ac8d90a106d8d634
- Full Text :
- https://doi.org/10.1016/s0969-2126(01)00264-7