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Engineered nanomaterials and human health: Part 2. Applications and nanotoxicology (IUPAC Technical Report)
- Source :
- Pure and Applied Chemistry. 90:1325-1356
- Publication Year :
- 2018
- Publisher :
- Walter de Gruyter GmbH, 2018.
-
Abstract
- Research on engineered nanomaterials (ENM) has progressed rapidly from the very early stages of studying their unique, size-dependent physicochemical properties and commercial exploration to the development of products that influence our everyday lives. We have previously reviewed various methods for synthesis, surface functionalization, and analytical characterization of ENM in a publication titled ‘Engineered Nanomaterials: Preparation, Functionalization and Characterization’. In this second, inter-linked document, we first provide an overview of important applications of ENM in products relevant to human healthcare and consumer goods, such as food, textiles, and cosmetics. We then highlight the challenges for the design and development of new ENM for bio-applications, particularly in the rapidly developing nanomedicine sector. The second part of this document is dedicated to nanotoxicology studies of ENM in consumer products. We describe the various biological targets where toxicity may occur, summarize the four nanotoxicology principles, and discuss the need for careful consideration of the biodistribution, degradation, and elimination routes of nanosized materials before they can be safely used. Finally, we review expert opinions on the risk, regulation, and ethical aspects of using engineered nanomaterials in applications that may have direct or indirect impact on human health or our environment.
- Subjects :
- Chemistry
nanoparticle
General Chemical Engineering
Engineered nanomaterials
nano-toxicology
regulation
02 engineering and technology
General Chemistry
anomaterial
010402 general chemistry
021001 nanoscience & nanotechnology
nanomedicine
01 natural sciences
0104 chemical sciences
Human health
Risk analysis (engineering)
Nanotoxicology
Nanomedicine
0210 nano-technology
Indirect impact
nano-products
Subjects
Details
- ISSN :
- 13653075 and 00334545
- Volume :
- 90
- Database :
- OpenAIRE
- Journal :
- Pure and Applied Chemistry
- Accession number :
- edsair.doi.dedup.....2fc16f9441e08d197a9b487cd458979a