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A Rare Case of Posterior Fossa Tumor and Central Precocious Puberty: Case Presentation and Review of the Literature
- Source :
- Neurology International, Vol 13, Iss 53, Pp 535-540 (2021), Neurology International
- Publication Year :
- 2021
- Publisher :
- MDPI AG, 2021.
-
Abstract
- Central precocious puberty (CPP) is a condition that causes early gonadotropin-dependent sexual development; CPP is idiopathic in girls in most cases, whereas more than 50% of boys have an identifiable etiology. We conducted a qualitative systematic review following the ENTREQ (enhancing transparency in reporting the synthesis of qualitative research) framework. A search was made in MEDLINE/Pubmed and MeSH Database using the terms “precocious puberty” AND “brain tumor” OR “posterior fossa tumor” OR “cerebellar tumor” OR “infratentorial tumor”, identifying five cases of pediatric patients with infratentorial tumors and CPP and a case of cerebellar ganglioglioma without hypothalamic−pituitary−gonadal axis involvement and/or intracranial hypertension. Our work highlights the importance of a multidisciplinary approach and extensive central nervous system imaging for patients presenting with CPP in order to detect possible tumor association. Moreover, we believe that this manuscript could contribute to stimulate other research because the exact mechanism of CPP in infratentorial brain lesions has not been understood yet.
- Subjects :
- Pediatrics
medicine.medical_specialty
Central nervous system
Central precocious puberty
MEDLINE
Brain tumor
Case Report
Neurosciences. Biological psychiatry. Neuropsychiatry
Ganglioglioma
medicine
Precocious puberty
neuroradiology
Internal medicine
ganglioglioma
Neuroradiology
business.industry
medicine.disease
RC31-1245
medicine.anatomical_structure
Etiology
Medicine
Neurology (clinical)
SNC
business
CPP
RC321-571
Subjects
Details
- Language :
- English
- ISSN :
- 20358377
- Volume :
- 13
- Issue :
- 53
- Database :
- OpenAIRE
- Journal :
- Neurology International
- Accession number :
- edsair.doi.dedup.....30081ff79334897db0a11256b3c42984