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Management of Cardiac Involvement Associated With Neuromuscular Diseases: A Scientific Statement From the American Heart Association
- Source :
- Circulation. 136(13)
- Publication Year :
- 2017
-
Abstract
- For many neuromuscular diseases (NMDs), cardiac disease represents a major cause of morbidity and mortality. The management of cardiac disease in NMDs is made challenging by the broad clinical heterogeneity that exists among many NMDs and by limited knowledge about disease-specific cardiovascular pathogenesis and course-modifying interventions. The overlay of compromise in peripheral muscle function and other organ systems, such as the lungs, also makes the simple application of endorsed adult or pediatric heart failure guidelines to the NMD population problematic. In this statement, we provide background on several NMDs in which there is cardiac involvement, highlighting unique features of NMD-associated myocardial disease that require clinicians to tailor their approach to prevention and treatment of heart failure. Undoubtedly, further investigations are required to best inform future guidelines on NMD-specific cardiovascular health risks, treatments, and outcomes.
- Subjects :
- medicine.medical_specialty
Neuromuscular disease
Cardiovascular health
Population
Cardiomyopathy
Psychological intervention
Disease
030204 cardiovascular system & hematology
03 medical and health sciences
0302 clinical medicine
Muscular Diseases
Risk Factors
Physiology (medical)
medicine
Humans
Myotonic Dystrophy
Intensive care medicine
education
Peripheral muscle
education.field_of_study
business.industry
American Heart Association
Neuromuscular Diseases
medicine.disease
Muscular Dystrophy, Emery-Dreifuss
United States
Muscular Dystrophy, Duchenne
Muscular Dystrophies, Limb-Girdle
Friedreich Ataxia
Heart failure
Barth Syndrome
Physical therapy
Cardiology and Cardiovascular Medicine
business
Cardiomyopathies
030217 neurology & neurosurgery
Myopathies, Structural, Congenital
Subjects
Details
- ISSN :
- 15244539
- Volume :
- 136
- Issue :
- 13
- Database :
- OpenAIRE
- Journal :
- Circulation
- Accession number :
- edsair.doi.dedup.....302c01510f14cbe85500d0a8cb5312e3