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Involvement of tgf-a, rock1, dock2 and caveolin-1 in osteoarthritis pathogenesis

Authors :
A. Bei
E. Chatziliadou
L. Takacs
Stephanie Dubos
Michalis Zervakis
Dimitris Kafetzopoulos
Aspasia Tsezou
Vassilios Papanikolaou
C. Zoumadakis
Konstantinos N. Malizos
Kalliopi Kalantzaki
Vasiliki Gkretsi
Source :
Osteoarthritis and Cartilage. 22
Publication Year :
2014
Publisher :
Elsevier BV, 2014.

Abstract

Περίληψη: Osteoarthritis (OA) is a debilitating disease of the joints characterized by cartilage degradation. To date there is no available pharmacological treatment to inhibit disease progression neither is there a suitable biomarker for early disease prognosis. The aim of the present study was to investigate the molecular pathways involved between four identified OA susceptibility genes and their role in OA pathogenesis. Presented on: Osteoarthritis and Cartilage

Details

ISSN :
10634584
Volume :
22
Database :
OpenAIRE
Journal :
Osteoarthritis and Cartilage
Accession number :
edsair.doi.dedup.....30317c98db4a3a5b73ec40b893a38e21
Full Text :
https://doi.org/10.1016/j.joca.2014.02.270