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The neutrophil-to-lymphocyte ratio in complete blood cell count may be an available marker for active adult-onset Still's disease
The neutrophil-to-lymphocyte ratio in complete blood cell count may be an available marker for active adult-onset Still's disease
- Source :
- Современная ревматология, Vol 14, Iss 4, Pp 65-69 (2020)
- Publication Year :
- 2020
- Publisher :
- IMA-PRESS LLC, 2020.
-
Abstract
- In clinical practice, acute-phase protein measurements during inflammation are usually used to monitor the activity and severity of adult-onset Still's disease (AOSD).Objective: to study the possibility of using the neutrophil-to-lymphocyte ratio (NLR) in complete blood cell count as a marker for the activity and severity of AOSD in clinical practice.Patients and methods. The investigation enrolled 48 patients (29 females and 19 males; mean age, 32.8±12.5 years) with active AOSD, who met the criteria devised by M. Yamaguchi et al. Along with standard clinical and laboratory parameters and systemic scores, NLR was calculated in complete blood cell count.Results and discussion. There was a statistically significant correlation of NLR with the level of CRP (r=0.532), ferritin (r=0.43), ESR (r=0.40), and the systemic score reflecting the severity of the disease (r=0.449), which allows NLR to be regarded as a tool that is convenient to assess the activity and severity of AOSD in clinical practice.Conclusion. The findings have shown the good sensitivity and specificity of NLR, which indicates the possibility of using the latter as an available marker for assessing the activity and severity of AOSD in clinical practice.
- Subjects :
- Adult-onset Still's disease
medicine.medical_specialty
Immunology
030204 cardiovascular system & hematology
Gastroenterology
03 medical and health sciences
0302 clinical medicine
Rheumatology
c-reactive protein
neutrophil-to-lymphocyte ratio
Internal medicine
Immunology and Allergy
Medicine
Pharmacology (medical)
Neutrophil to lymphocyte ratio
medicine.diagnostic_test
biology
business.industry
C-reactive protein
ferritin
Mean age
Clinical Practice
nervous system
030220 oncology & carcinogenesis
Erythrocyte sedimentation rate
biology.protein
erythrocyte sedimentation rate
business
adult-onset still's disease
Subjects
Details
- Language :
- Russian
- ISSN :
- 19967012
- Volume :
- 14
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Современная ревматология
- Accession number :
- edsair.doi.dedup.....315a2fe47445c4fefc4765ebaa426701