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Lower tumorigenesis without life extension in rats receiving lifelong deep ocean minerals

Authors :
Suchada Saovieng
Chiao Nan Chen
Jinfu Wu
Chih Yang Huang
Ahmad Alkhatib
Chia-Hua Kuo
Matthew J. Higgins
Mallikarjuna Korivi
Wei Horng Jean
Source :
Cancer Medicine, Vol 9, Iss 11, Pp 3964-3973 (2020), Cancer Medicine
Publication Year :
2020
Publisher :
Wiley, 2020.

Abstract

Naturally occurring tumor in animals receiving high minerals from deep oceans (DOM: hardness 600 mg/L) from 6 months of age until natural death was firstly assessed in 200 Sprague Dawley rats, randomized into four groups: Control (C), DOM (D), Fructose (F), and Fructose + DOM (FD). Fructose drink contained 11% fructose. Tumor incidence (necropsy at death) in the D group was ~40% lower than that in the C group (P<br />Tumor incidence increases with advancing aging. Lifelong supplementation of deep ocean minerals significantly suppresses age‐associated tumorigenesis. This tumor‐suppressive action is associated with preventing weight gain and increasing spontaneous physical activity during the first two‐thirds period of life.

Details

Language :
English
ISSN :
20457634
Volume :
9
Issue :
11
Database :
OpenAIRE
Journal :
Cancer Medicine
Accession number :
edsair.doi.dedup.....316b3f9d042c83132733513ac9d1855b