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Lower tumorigenesis without life extension in rats receiving lifelong deep ocean minerals
- Source :
- Cancer Medicine, Vol 9, Iss 11, Pp 3964-3973 (2020), Cancer Medicine
- Publication Year :
- 2020
- Publisher :
- Wiley, 2020.
-
Abstract
- Naturally occurring tumor in animals receiving high minerals from deep oceans (DOM: hardness 600 mg/L) from 6 months of age until natural death was firstly assessed in 200 Sprague Dawley rats, randomized into four groups: Control (C), DOM (D), Fructose (F), and Fructose + DOM (FD). Fructose drink contained 11% fructose. Tumor incidence (necropsy at death) in the D group was ~40% lower than that in the C group (P<br />Tumor incidence increases with advancing aging. Lifelong supplementation of deep ocean minerals significantly suppresses age‐associated tumorigenesis. This tumor‐suppressive action is associated with preventing weight gain and increasing spontaneous physical activity during the first two‐thirds period of life.
- Subjects :
- Male
0301 basic medicine
Cancer Research
tumor
Carcinogenesis
Oceans and Seas
Physiology
Normal aging
medicine.disease_cause
lcsh:RC254-282
fructose
Rats, Sprague-Dawley
03 medical and health sciences
chemistry.chemical_compound
Life Expectancy
0302 clinical medicine
Tumor Expansion
Sprague dawley rats
Animals
Medicine
cancer
Radiology, Nuclear Medicine and imaging
Mass gain
glutathione
Original Research
Cancer Biology
Minerals
business.industry
Fructose
Neoplasms, Experimental
Glutathione
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Rats
030104 developmental biology
Oncology
chemistry
Sweetening Agents
030220 oncology & carcinogenesis
Natural source
Female
business
lifespan
Subjects
Details
- Language :
- English
- ISSN :
- 20457634
- Volume :
- 9
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- Cancer Medicine
- Accession number :
- edsair.doi.dedup.....316b3f9d042c83132733513ac9d1855b