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Supplementary Table 1 and 2 from First-in-Human Phase I Study of GSK2126458, an Oral Pan-Class I Phosphatidylinositol-3-Kinase Inhibitor, in Patients with Advanced Solid Tumor Malignancies

Authors :
Razelle Kurzrock
Shannon R. Morris
Thomas A. Lampkin
Deborah A. Smith
Laurel Adams
Michael Durante
Joseph F. Kleha
Neeraj Agarwal
Emily Bergsland
E. Claire Dees
Theresa L. Werner
Petronella O. Witteveen
Jennifer Specht
Ruud van der Noll
Jan H.M. Schellens
David Hong
Rahul Aggarwal
Pamela Munster
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Supplementary Table 1. Pharmacokinetic Parameters on Day 1 Following Once daily and Twice Daily Administration of GSK458 Supplementary Table 2. Best Objective Tumor Response by Dose Level (supplementary)

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....31cc3113a08b14c37c80c2acf0e81ea6
Full Text :
https://doi.org/10.1158/1078-0432.22461510