Back to Search
Start Over
The Plant Anaphase-Promoting Complex/Cyclosome
- Source :
- ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY
- Publication Year :
- 2022
- Publisher :
- Annual Reviews, 2022.
-
Abstract
- The anaphase-promoting complex/cyclosome (APC/C) represents a large multisubunit E3-ubiquitin ligase complex that controls the unidirectional progression through the cell cycle by the ubiquitination of specific target proteins, marking them for proteasomal destruction. Although the APC/C's role is largely conserved among eukaryotes, its subunit composition and target spectrum appear to be species specific. In this review, we focus on the plant APC/C complex, whose activity correlates with different developmental processes, including polyploidization and gametogenesis. After an introduction into proteolytic control by ubiquitination, we discuss the composition of the plant APC/C and the essential nature of its core subunits for plant development. Subsequently, we describe the APC/C activator subunits and interactors, most being plant specific. Finally, we provide a comprehensive list of confirmed and suspected plant APC/C target proteins. Identification of growth-related targets might offer opportunities to increase crop yield and resilience of plants to climate change by manipulating APC/C activity.
- Subjects :
- cell division
proteasomal degradation
cell cycle progression
Cell Cycle
Ubiquitination
Biology and Life Sciences
food and beverages
Cell Cycle Proteins
anaphase-promoting complex/cyclosome
Cell Biology
Plants
ubiquitination
Anaphase-Promoting Complex-Cyclosome
Anaphase
Ubiquitins
Developmental Biology
Subjects
Details
- ISSN :
- 15308995 and 10810706
- Volume :
- 38
- Database :
- OpenAIRE
- Journal :
- Annual Review of Cell and Developmental Biology
- Accession number :
- edsair.doi.dedup.....31eae98ef28feb2bf748ae14ad0d9e94