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Characterization of single nucleotide polymorphisms for a forward genetics approach using genetic crosses in C57BL/6 and BALB/c substrains of mice

Authors :
Ikuo, Miura
Yoshiaki, Kikkawa
Shumpei P, Yasuda
Akiko, Shinogi
Daiki, Usuda
Vivek, Kumar
Joseph S, Takahashi
Masaru, Tamura
Hiroshi, Masuya
Shigeharu, Wakana
Source :
Experimental Animals. 71:240-251
Publication Year :
2022
Publisher :
Japanese Association for Laboratory Animal Science, 2022.

Abstract

Forward genetics is a powerful approach based on chromosomal mapping of phenotypes and has successfully led to the discovery of many mouse mutations in genes responsible for various phenotypes. Although crossing between genetically remote strains can produce F

Details

ISSN :
18817122 and 13411357
Volume :
71
Database :
OpenAIRE
Journal :
Experimental Animals
Accession number :
edsair.doi.dedup.....31fc1f0cee957196da6102115784b355
Full Text :
https://doi.org/10.1538/expanim.21-0181