Back to Search
Start Over
Unravelling the potential mechanisms behind hospitalization-associated disability in older patients
- Source :
- BMC Geriatrics, 16:59. BioMed Central Ltd., BMC geriatrics, 16(1). BioMed Central, BMC geriatrics, 16:59. BioMed Central, BMC Geriatrics
- Publication Year :
- 2016
- Publisher :
- BioMed Central, 2016.
-
Abstract
- BACKGROUND: Over 30 % of older patients experience hospitalization-associated disability (HAD) (i.e., loss of independence in Activities of Daily Living (ADLs)) after an acute hospitalization. Despite its high prevalence, the mechanisms that underlie HAD remain elusive. This paper describes the protocol for the Hospital-Associated Disability and impact on daily Life (Hospital-ADL) study, which aims to unravel the potential mechanisms behind HAD from admission to three months post-discharge.METHODS/DESIGN: The Hospital-ADL study is a multicenter, observational, prospective cohort study aiming to recruit 400 patients aged ≥70 years that are acutely hospitalized at departments of Internal Medicine, Cardiology or Geriatrics, involving six hospitals in the Netherlands. Eligible are patients hospitalized for at least 48 h, without major cognitive impairment (Mini Mental State Examination score ≥15), who have a life expectancy of more than three months, and without disablement in all six ADLs. The study will assess possible cognitive, behavioral, psychosocial, physical, and biological factors of HAD. Data will be collected through: 1] medical and demographical data; 2] personal interviews, which includes assessment of cognitive impairment, behavioral and psychosocial functioning, physical functioning, and health care utilization; 3] physical performance tests, which includes gait speed, hand grip strength, balance, bioelectrical impedance analysis (BIA), and an activity tracker (Fitbit Flex), and; 4] analyses of blood samples to assess inflammatory and metabolic markers. The primary endpoint is additional disabilities in ADLs three months post-hospital discharge compared to ADL function two weeks prior to hospital admission. Secondary outcomes are health care utilization, health-related quality of life (HRQoL), physical performance tests, and mortality. There will be at least five data collection points; within 48 h after admission (H1), at discharge (H3), and at one (P1; home visit), two (P2; by telephone) and three months (P3; home visit) post-discharge. If the patient is admitted for more than five days, additional measurements will be planned during hospitalization on Monday, Wednesday, and Friday (H2).DISCUSSION: The Hospital-ADL study will provide information on cognitive, behavioral, psychosocial, physical, and biological factors associated with HAD and will be collected during and following hospitalization. These data may inform new interventions to prevent or restore hospitalization-associated disability.
- Subjects :
- Male
Gerontology
medicine.medical_specialty
Activities of daily living
medicine.medical_treatment
Psychological intervention
Hospitalization-associated disability
Study Protocol
03 medical and health sciences
0302 clinical medicine
Quality of life (healthcare)
Functional decline
Activities of Daily Living
Older patients
Prevalence
Humans
Medicine
Disabled Persons
Prospective Studies
030212 general & internal medicine
Acute hospitalization
Prospective cohort study
Geriatric Assessment
Aged
Netherlands
Geriatrics
Rehabilitation
business.industry
Mental Disorders
Hospitalization
Quality of Life
Physical therapy
Female
Geriatrics and Gerontology
business
Psychosocial
human activities
030217 neurology & neurosurgery
Cohort study
Subjects
Details
- Language :
- English
- ISSN :
- 14712318
- Volume :
- 16
- Database :
- OpenAIRE
- Journal :
- BMC geriatrics
- Accession number :
- edsair.doi.dedup.....3201b72812e12c0fb800e45bd2a785eb