Diastereoselective Synthesis of β-Substituted α-Hydroxyphosphinates Through Hydrophosphinylation of α-Heteroatom-Substituted Aldehydes

The diastereoselective synthesis of β-substituted α-hydroxyphosphinates was achieved by hydrophosphinylation of α-oxy aldehydes and α-amino aldehydes with ethyl allylphosphinate catalyzed by lithium phenoxide.