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Abnormal Cardiovascular Findings in Acute Pancreatitis: Are They Associated with Disease Severity?
- Source :
- Revista de investigaci�n Cl�nica. 69
- Publication Year :
- 2017
- Publisher :
- Publicidad Permanyer, SLU, 2017.
-
Abstract
- Background: Acute pancreatitis (AP), a disease that commonly requires in-hospital treatment, has been associated with a high incidence of abnormal cardiovascular findings (ACFs). We conducted a prospective study to explore the association of these findings with severity of the disease. Methods: Adult patients with AP diagnosis were prospectively enrolled in an observational study during an 8-month period in a tertiary care center. AP and its severity were defined according to the Revised Atlanta Classification of AP. Subjects were submitted to electrocardiographic, echocardiographic, and serologic testing during the acute period and a 3-month follow-up. The incidence of ACF was compared between two groups: (1) Mild and (2) moderate/severe cases. Results: Twenty-seven patients (mean age 48 ± 17 years) with AP were enrolled; 15 (55%) had mild and 12 (45%) had moderate/severe AP. During the acute episode, 67% had increased pro-brain natriuretic peptide levels; 52% had abnormal electrocardiographic findings; 48% had abnormal echocardiographic findings; and 18% had increased troponin I levels. There was no significant difference in the incidence of ACF between mild and moderate/severe groups. Nineteen patients (70%) had repeated follow-up testing, and most of the initial ACF did not persist. Conclusion: ACFs occur in an important proportion of patients during AP episodes. Future research should continue to focus in the association of ACFs and the severity of the disease.
- Subjects :
- Adult
Male
0301 basic medicine
medicine.medical_specialty
medicine.drug_class
Disease
Severity of Illness Index
Serology
Tertiary Care Centers
Electrocardiography
03 medical and health sciences
Internal medicine
Natriuretic Peptide, Brain
Troponin I
Natriuretic peptide
medicine
Humans
Prospective Studies
Prospective cohort study
Aged
medicine.diagnostic_test
business.industry
Incidence
Incidence (epidemiology)
General Medicine
Middle Aged
medicine.disease
Peptide Fragments
030104 developmental biology
Pancreatitis
Cardiovascular Diseases
Echocardiography
Acute Disease
Acute pancreatitis
Female
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 00348376
- Volume :
- 69
- Database :
- OpenAIRE
- Journal :
- Revista de investigaci�n Cl�nica
- Accession number :
- edsair.doi.dedup.....32b7f97073dda23a18ba6dcc78a66ccc
- Full Text :
- https://doi.org/10.24875/ric.17002361