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MOESM3 of BRD4 bimodal binding at promoters and drug-induced displacement at Pol II pause sites associates with I-BET sensitivity

Authors :
P. Khoueiry
A. Ward Gahlawat
M. Petretich
A. Michon
D. Simola
E. Lam
E. Furlong
V. Benes
M. Dawson
R. Prinjha
G. Drewes
P. Grandi
Publication Year :
2019
Publisher :
figshare, 2019.

Abstract

Additional file 3: Figure S2. Barplot with the number of peaks called for each condition and for both cell lines (a) for all peaks and (b) for peaks overlapping a TSS − 1 Kb or a TSS + 1 Kb. (c) Stacked barplot showing the percentage of peaks falling in TSS −/+ 1 Kb (blue), H3K27ac marked regions excluding TSS −/+ 1 Kb (orange) and other intergenic or genic regions excluding TSS −/+ 1 Kb and H3K27ac marked sites (gray) after treating cells in DMSO, 50 nM, 500 nM or 5000 nM I-BET151.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....32d14a64e62e3443bdd729ff11ed3de0
Full Text :
https://doi.org/10.6084/m9.figshare.8480090