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Diastereoselective Johnson-Corey-Chaykovsky trifluoroethylidenation
- Source :
- Chemical communications (Cambridge, England). 51(66)
- Publication Year :
- 2015
-
Abstract
- (2,2,2-Trifluoroethyl)diphenylsulfonium triflate was found to be an efficient ylide reagent for the Johnson–Corey–Chaykovsky reaction to afford trifluoromethyl epoxides, cyclopropanes and aziridines. Interestingly, excellent but different diastereoselectivity was observed for these transformations. Both trifluoromethyl epoxides and cyclopropanes were obtained with trans-selectivity, whereas aziridines were obtained with cis-selectivity.
- Subjects :
- chemistry.chemical_classification
Cyclopropanes
Trifluoromethyl
Hydrocarbons, Fluorinated
Chemistry
Aziridines
Metals and Alloys
Stereoisomerism
General Chemistry
Catalysis
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
chemistry.chemical_compound
Ylide
Reagent
Materials Chemistry
Ceramics and Composites
Organic chemistry
Epoxy Compounds
Trifluoromethanesulfonate
Subjects
Details
- ISSN :
- 1364548X
- Volume :
- 51
- Issue :
- 66
- Database :
- OpenAIRE
- Journal :
- Chemical communications (Cambridge, England)
- Accession number :
- edsair.doi.dedup.....32ec7e8cada19089d9e4f7e95a546cef