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Evaluation of virucidal activity of fabrics using feline coronavirus
- Source :
- Journal of Virological Methods
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Severe Acute Respiratory Syndrome Coronavirus type 2 (SARS-CoV-2) is an enveloped RNA virus responsible for the 2019 coronavirus disease (COVID-19) that represents a global health threat, causing an ongoing pandemic in many countries and territories. WHO recommendations emphasize the importance of all personal protective equipment (PPE) that can interrupt COVID-19 transmission. The textile industry and scientists are developing hygienic fabrics by the addition of or treatment with various antimicrobial and antiviral compounds. Methods for determining the antiviral activity of fabrics are reported in the International Standards Organization (ISO) 18184 (2019) guidelines. Three different fabric samples treated with silver derivate, copper derivative and a not treated cotton fabric used as control were examined and put in contact with a suspension of feline coronavirus (FCoV). After 2 h of incubation a significant decrease of viral titer, as high as 3.25 log10 Tissue Culture Infectious Dose (TCID)50/50 μl, in feline cells was observed in treated fabrics, with respect to not treated fabrics. In this study, we optimized laboratory methods to evaluate the virucidal activity of silver- and copper treated cotton- based fabrics against coronavirus, using FCoV suitable as a surrogate of SARS-CoV-2 but safe for laboratory technicians.
- Subjects :
- 0301 basic medicine
FCoV, Feline coronavirus
Feline coronavirus
cpe, cytopathic effect
medicine.disease_cause
ANOVA, one-way Analysis of Variance
ISO, International Standards Organization
COVID-19, 2019 coronavirus disease
Coronavirus
SARS-CoV-2, Severe Acute Respiratory Syndrome Coronavirus type 2
Textiles
Infectious dose
Viral Load
Antimicrobial
Titer
WHO, World Health Organisation
Viral load
PPE, personal protective equipment
Silver
In vitro test
Fabrics
Coronavirus disease 2019 (COVID-19)
Cell Survival
Short Communication
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
030106 microbiology
Biology
Virucidal activity
Antiviral Agents
Cell Line
TCID, Tissue Culture Infectious Dose
03 medical and health sciences
Virology
D-MEM, Dulbecco's Modified Eagle Medium
parasitic diseases
medicine
Animals
Humans
Coronavirus, Feline
Personal Protective Equipment
SARS-CoV-2
technology, industry, and agriculture
COVID-19
030104 developmental biology
Cats
CRFK, Crandell-Rees Feline Kidney Cell
Cell culture
SD, standard deviation
Copper
Subjects
Details
- ISSN :
- 01660934
- Volume :
- 295
- Database :
- OpenAIRE
- Journal :
- Journal of Virological Methods
- Accession number :
- edsair.doi.dedup.....330b4442667b2ece3d96c54776f20c2e