Difluoromethylation and gem-difluorocyclopropenation with difluorocarbene generated by decarboxylation

Authors :: Jian Zheng
Xiao-Yun Deng
Ji-Chang Xiao
Jin-Hong Lin
Source :: Chemical Communications. 51:8805-8808
Publication Year :: 2015
Publisher :: Royal Society of Chemistry (RSC), 2015.
Abstract: Difluoromethylation of the activated X-H bond (X = N, O and S) and aliphatic thiols, and gem-difluorocyclopropenation of alkynes with difluorocarbene generated in situ from difluoromethylene phosphobetaine (Ph3P(+)CF2CO2(-)) by decarboxylation occurred smoothly without the presence of any base or other additives.

Subjects :: chemistry.chemical_classification
Hydrocarbons, Fluorinated
Molecular Structure
Base (chemistry)
Difluorocarbene
Chemistry
Decarboxylation
Metals and Alloys
General Chemistry
Photochemistry
Catalysis
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
chemistry.chemical_compound
Alkynes
Polymer chemistry
Materials Chemistry
Ceramics and Composites
Sulfhydryl Compounds

Tools