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Retraction Note to: Diffusion-weighted MR imaging of locally advanced breast carcinoma: the optimal time window of predicting the early response to neoadjuvant chemotherapy
- Source :
- Cancer Imaging, Cancer Imaging, Vol 21, Iss 1, Pp 1-1 (2021)
- Publication Year :
- 2021
- Publisher :
- BioMed Central, 2021.
-
Abstract
- Background It is very difficult to predict the early response to NAC only on the basis of change in tumor size. ADC value derived from DWI promises to be a valuable parameter for evaluating the early response to treatment. This study aims to establish the optimal time window of predicting the early response to neoadjuvant chemotherapy (NAC) for different subtypes of locally advanced breast carcinoma using diffusion-weighted imaging (DWI). Methods We conducted an institutional review board-approved prospective clinical study of 142 patients with locally advanced breast carcinoma. All patients underwent conventional MR and DW examinations prior to treatment and after first, second, third, fourth, sixth and eighth cycle of NAC. The response to NAC was classified into a pathologic complete response (pCR) and a non-pCR group. DWI parameters were compared between two groups, and the optimal time window for predicting tumor response was established for each chemotherapy regimen. Results For all the genomic subtypes, there were significant differences in baseline ADC value between pCR and non-pCR group (p
- Subjects :
- Oncology
Adult
Neoadjuvant chemotherapy (NAC)
medicine.medical_specialty
Time Factors
Therapeutic response
medicine.medical_treatment
Breast carcinoma
R895-920
Locally advanced
Breast Neoplasms
Medical physics. Medical radiology. Nuclear medicine
Internal medicine
Medicine
Humans
Radiology, Nuclear Medicine and imaging
Magnetic resonance imaging (MRI)
Prospective Studies
Time point
Diffusion-Weighted MR Imaging
RC254-282
Chemotherapy
Radiological and Ultrasound Technology
Tumor size
business.industry
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Diffusion-weighted imaging (DWI)
General Medicine
Middle Aged
Time optimal
Chemotherapy regimen
Neoadjuvant Therapy
Retraction Note
Diffusion Magnetic Resonance Imaging
Treatment Outcome
Chemotherapy, Adjuvant
Female
business
Research Article
Subjects
Details
- Language :
- English
- ISSN :
- 14707330 and 17405025
- Volume :
- 21
- Database :
- OpenAIRE
- Journal :
- Cancer Imaging
- Accession number :
- edsair.doi.dedup.....337f6b96dc14b41accfdfc03aae5172d