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Lung recruitment in the prone position after cardiac surgery: a randomised controlled study

Authors :
S. Lindgren
Andreas Wallinder
Erik Houltz
Anders Thorén
Andreas Martinsson
Source :
British Journal of Anaesthesia. 126:1067-1074
Publication Year :
2021
Publisher :
Elsevier BV, 2021.

Abstract

Background Atelectasis after cardiac surgery is common and promotes ventilation/perfusion mismatch, infection, and delayed discharge from critical care. Recruitment manoeuvres are often performed to reduce atelectasis. In severe respiratory failure, recruitment manoeuvres in the prone position may increase oxygenation, survival, or both. We compared the effects of recruitment manoeuvres in the prone vs supine position on lung aeration and oxygenation in cardiac surgical patients. Methods Subjects were randomised to recruitment manoeuvres (40 cm H2O peak inspiratory pressure and 20 cm H2O PEEP for 30 s) in either the prone or supine position after uncomplicated cardiac surgery. The co-primary endpoints were lung aeration (end-expiratory lung volume measured by electrical impedance tomography (arbitrary units [a.u.]) and lung oxygenation (ratio of arterial oxygen partial pressure to fractional inspired oxygen [Pao2/FiO2 ratio]). Secondary outcomes included postoperative oxygen requirement and adverse events. Results Thirty subjects (27% female; age, 48–81 yr) were recruited. Dorsal lung tidal volume was higher after prone recruitment manoeuvres (363 a.u.; 95% confidence intervals [CI], 283–443; n=15) after extubation, compared with supine recruitment manoeuvres (212 a.u.; 95% CI, 170–254; n=15; P Conclusions Recruitment manoeuvres in the prone position after cardiac surgery improve lung aeration and oxygenation. Clinical trial registration NCT03009331.

Details

ISSN :
00070912
Volume :
126
Database :
OpenAIRE
Journal :
British Journal of Anaesthesia
Accession number :
edsair.doi.dedup.....339b01bc4fbf5d0bce3e966617fca22a
Full Text :
https://doi.org/10.1016/j.bja.2020.12.039