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Lung recruitment in the prone position after cardiac surgery: a randomised controlled study
- Source :
- British Journal of Anaesthesia. 126:1067-1074
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Background Atelectasis after cardiac surgery is common and promotes ventilation/perfusion mismatch, infection, and delayed discharge from critical care. Recruitment manoeuvres are often performed to reduce atelectasis. In severe respiratory failure, recruitment manoeuvres in the prone position may increase oxygenation, survival, or both. We compared the effects of recruitment manoeuvres in the prone vs supine position on lung aeration and oxygenation in cardiac surgical patients. Methods Subjects were randomised to recruitment manoeuvres (40 cm H2O peak inspiratory pressure and 20 cm H2O PEEP for 30 s) in either the prone or supine position after uncomplicated cardiac surgery. The co-primary endpoints were lung aeration (end-expiratory lung volume measured by electrical impedance tomography (arbitrary units [a.u.]) and lung oxygenation (ratio of arterial oxygen partial pressure to fractional inspired oxygen [Pao2/FiO2 ratio]). Secondary outcomes included postoperative oxygen requirement and adverse events. Results Thirty subjects (27% female; age, 48–81 yr) were recruited. Dorsal lung tidal volume was higher after prone recruitment manoeuvres (363 a.u.; 95% confidence intervals [CI], 283–443; n=15) after extubation, compared with supine recruitment manoeuvres (212 a.u.; 95% CI, 170–254; n=15; P Conclusions Recruitment manoeuvres in the prone position after cardiac surgery improve lung aeration and oxygenation. Clinical trial registration NCT03009331.
- Subjects :
- Male
Time Factors
Supine position
Atelectasis
Peak inspiratory pressure
Patient Positioning
Prone Position
Supine Position
Tidal Volume
medicine
Humans
Lung volumes
Cardiac Surgical Procedures
Lung
Tidal volume
Aged
Aged, 80 and over
business.industry
Oxygen Inhalation Therapy
Oxygenation
Middle Aged
respiratory system
medicine.disease
Oxygen
Prone position
Anesthesiology and Pain Medicine
Respiratory failure
Anesthesia
Airway Extubation
Female
Lung Volume Measurements
business
Subjects
Details
- ISSN :
- 00070912
- Volume :
- 126
- Database :
- OpenAIRE
- Journal :
- British Journal of Anaesthesia
- Accession number :
- edsair.doi.dedup.....339b01bc4fbf5d0bce3e966617fca22a
- Full Text :
- https://doi.org/10.1016/j.bja.2020.12.039