Figure S6 from MYCN-Amplified Neuroblastoma Is Addicted to Iron and Vulnerable to Inhibition of the System Xc-/Glutathione Axis

Authors :: Anthony C. Faber
Sosipatros A. Boikos
Jennifer E. Koblinski
John Glod
Mikhail G. Dozmorov
Janina P. Lewis
Kimberly Swift
Sivapriya Ramamoorthy
Madhavi Puchalapalli
Bin Hu
Benjamin R. Belvin
Krista M. Powell
Colin M. Coon
Mayuri Shende
Carter K. Fairchild
Richard Kurupi
Sheeba Jacob
JinYang Cai
Konstantinos V. Floros
Publication Year :: 2023
Publisher :: American Association for Cancer Research (AACR), 2023.
Abstract: Figure S6. Overexpression of c-Myc in neuroblastomas increases the expression of transferrin receptor 1, the system Xc- subunit SLC3A2, and sensitizes neuroblastomas to auranofin.

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