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IMI 2021 Yearly Digest
- Source :
- Investigative Ophthalmology and Visual Science, 62, Investigative Ophthalmology and Visual Science, 62, 5, Investigative Ophthalmology & Visual Science
- Publication Year :
- 2021
- Publisher :
- Association for Research in Vision and Ophthalmology (ARVO), 2021.
-
Abstract
- Item does not contain fulltext PURPOSE: The International Myopia Institute (IMI) Yearly Digest highlights new research considered to be of importance since the publication of the first series of IMI white papers. METHODS: A literature search was conducted for articles on myopia between 2019 and mid-2020 to inform definitions and classifications, experimental models, genetics, interventions, clinical trials, and clinical management. Conference abstracts from key meetings in the same period were also considered. RESULTS: One thousand articles on myopia have been published between 2019 and mid-2020. Key advances include the use of the definition of premyopia in studies currently under way to test interventions in myopia, new definitions in the field of pathologic myopia, the role of new pharmacologic treatments in experimental models such as intraocular pressure-lowering latanoprost, a large meta-analysis of refractive error identifying 336 new genetic loci, new clinical interventions such as the defocus incorporated multisegment spectacles and combination therapy with low-dose atropine and orthokeratology (OK), normative standards in refractive error, the ethical dilemma of a placebo control group when myopia control treatments are established, reporting the physical metric of myopia reduction versus a percentage reduction, comparison of the risk of pediatric OK wear with risk of vision impairment in myopia, the justification of preventing myopic and axial length increase versus quality of life, and future vision loss. CONCLUSIONS: Large amounts of research in myopia have been published since the IMI 2019 white papers were released. The yearly digest serves to highlight the latest research and advances in myopia.
- Subjects :
- 0301 basic medicine
Refractive error
emmetropization
genetic structures
definitions
medicine.medical_treatment
Psychological intervention
spectacles
PROGRESSION
Sensory disorders Donders Center for Medical Neuroscience [Radboudumc 12]
0302 clinical medicine
Quality of life
genetics
cycloplegia
high myopia
Special Issue
EYE GROWTH
PREVALENCE
3. Good health
classification
Disease Progression
EXPRESSION
atropine
MEDLINE
orthokeratology
axial length
FORM-DEPRIVATION MYOPIA
Refraction, Ocular
03 medical and health sciences
REFRACTIVE DEVELOPMENT
Pathologic myopia
medicine
Humans
myopia
3125 Otorhinolaryngology, ophthalmology
interventions
clinical trials
business.industry
pathologic myopia
Orthokeratology
medicine.disease
eye diseases
contact lenses
Clinical trial
030104 developmental biology
management guidelines
ONSET
Quality of Life
RISK-FACTORS
030221 ophthalmology & optometry
Optometry
Normative
sense organs
business
Orthokeratologic Procedures
Subjects
Details
- ISSN :
- 15525783 and 01460404
- Volume :
- 62
- Database :
- OpenAIRE
- Journal :
- Investigative Opthalmology & Visual Science
- Accession number :
- edsair.doi.dedup.....3407e251da81cd959543a2deac8c85fb