TLR4 on hematopoietic cells is crucial for host defense against Klebsiella pneumonia but TLR2 is needed when bacterial numbers are high

Klebsiella species are opportunistic pathogens that can give rise to severe infections including pneumonia and sepsis. Typically, Klebsiella infections are nosocomial and mainly caused by Klebsiella pneumoniae, the medically most important species of the genus.