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Long term prognosis in patients with pulmonary hypertension undergoing catheter ablation for supraventricular tachycardia
- Source :
- Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021), Scientific Reports
- Publication Year :
- 2021
- Publisher :
- Springer Science and Business Media LLC, 2021.
-
Abstract
- Various forms of supraventricular tachycardia (SVT) occur in patients with severe pulmonary hypertension (PH). Despite the high efficacy of radiofrequency catheter ablation (RFCA) for SVT, insufficient data exist regarding patients with PH. Thirty SVTs in 23 PH patients (age 47 [35–60] years; mean pulmonary artery pressure 44 [32–50] mmHg) were analyzed. Procedural success rate, short- and long-term clinical outcomes, were evaluated during a median follow-up of 5.1 years. Single-procedure success rate was 83%; 94% (17/18) in typical atrial flutter, 73% (8/11) in atrial tachycardia (AT), and 100% (1/1) in atrioventricular nodal reentrant tachycardia. Antiarrhythmic drugs, serum brain natriuretic peptide levels and number of hospitalizations significantly decreased after RFCA than that before (p = 0.002, 0.04, and 0.002, respectively). Four patients had several procedures. After last RFCA, 12 patients had SVT and 8 patients died. Kaplan–Meier curves showed that patients with SVT after the last RFCA had a lower survival rate compared to those without (p = 0.0297). Multivariate analysis identified any SVT after the last RFCA as significant risk factor of mortality (hazard ratio: 9.31; p = 0.016). RFCA for SVT in patients with PH is feasible and effective in the short-term, but SVT is common during long-term follow-up and associated with lower survival.
- Subjects :
- Adult
Male
Tachycardia
medicine.medical_specialty
Hypertension, Pulmonary
Science
medicine.medical_treatment
Cardiology
Catheter ablation
Article
Medical research
Internal medicine
medicine.artery
Tachycardia, Supraventricular
Humans
Medicine
Survival rate
Atrial tachycardia
Retrospective Studies
Multidisciplinary
business.industry
Hazard ratio
Middle Aged
Prognosis
medicine.disease
Pulmonary hypertension
Survival Rate
Pulmonary artery
Catheter Ablation
Female
Supraventricular tachycardia
medicine.symptom
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 20452322
- Volume :
- 11
- Database :
- OpenAIRE
- Journal :
- Scientific Reports
- Accession number :
- edsair.doi.dedup.....347d0fac913bf6425ac2426bfac5e219