Back to Search
Start Over
Migraine improvement after spontaneous cervical artery dissection the Italian Project on Stroke in Young Adults (IPSYS)
- Publication Year :
- 2019
- Publisher :
- Springer-Verlag Italia s.r.l, 2019.
-
Abstract
- Objective: Whether migraine modifies after spontaneous cervical artery dissection (sCeAD) more than after other stroke etiologic subtypes has never been adequately investigated. Methods: In the setting of the Italian Project on Stroke in Young Adults (IPSYS), we compared the course of migraine before and after acute brain infarct in a group of migraine patients with sCeAD and a group of migraine patients whose ischemia was due to a cause other than CeAD (non-CeAD IS), matched by sex, age (± 3 years), and migraine subtype.We applied linear mixed models to evaluate pre-event vs post-event changes and differences between sCeAD and non-CeAD IS patients. Results: Eighty-seven patients per group (migraine without aura/migraine with aura, 67/20) qualified for the analysis. After the acute event, migraine headaches disappeared in 14.0% of CeAD patients vs 0.0% of non-CeAD IS patients (p ≤ 0.001). Migraine frequency (patients suffering at least 1 attack, from 93.1 to 80.5%, p = 0.001), pain intensity (from 6.7 ± 1.7 to 4.6 ± 2.6 in a 0 to 10 pain scale, p ≤ 0.001), and use of acute anti-migraine medications (patients taking at least 1 preparation, from 81.6 to 64.4%, p = 0.007) also improved significantly after CeAD as opposed to that observed after non-CeAD IS. Conclusion: The spontaneous improvement of migraine after sCeAD reinforces the hypothesis of a pathogenic link between the two conditions
- Subjects :
- Adult
Male
Migraine without Aura
medicine.medical_specialty
Neurology
Aura
Migraine with Aura
Remission, Spontaneous
LS5_11
Dermatology
Cervical artery dissection
Cervical artery dissection, Migraine, Stroke in young adults
03 medical and health sciences
Young Adult
Economica
Stroke in young adults
0302 clinical medicine
Risk Factors
Internal medicine
Medicine
Humans
030212 general & internal medicine
Young adult
Stroke
Migraine
LS4_7
Vertebral Artery Dissection
business.industry
Migraine. Spontaneus cervical dissection
General Medicine
Pain scale
Cerebral Infarction
medicine.disease
Migraine with aura
Stroke in young
Psychiatry and Mental health
adults Migraine
Italy
Case-Control Studies
Female
Neurology (clinical)
medicine.symptom
Headaches
business
030217 neurology & neurosurgery
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....3490fd329902e94b6d394e833b84a4e1