Back to Search
Start Over
Chronic Early-Stage Ocular Cicatricial Pemphigoid
- Source :
- Ophthalmic plastic and reconstructive surgery. 37(6)
- Publication Year :
- 2021
-
Abstract
- Ocular cicatricial pemphigoid (OCP) represents an insidious, autoimmune-mediated disease of the conjunctiva, initially presenting as chronic conjunctivitis and progressing to fibrosis, cicatrization, and eventually blindness secondary to corneal keratinization. This series reports 3 cases presenting with chronic conjunctivitis lasting an average of 10 years without cicatrix formation, ultimately diagnosed as OCP based on direct immunofluorescence of conjunctival biopsy samples. This chronic conjunctivitis without fibrosis suggests the possibility of an OCP subtype with a prolonged early stage or prodrome prior to cicatrization, which may benefit from early diagnosis and treatment to prevent complications of this disease.
- Subjects :
- medicine.medical_specialty
Conjunctiva
business.industry
Pemphigoid, Benign Mucous Membrane
General Medicine
Disease
Ocular Cicatricial Pemphigoid
medicine.disease
Conjunctivitis
Dermatology
eye diseases
Autoimmune Diseases
Prodrome
Cornea
Ophthalmology
medicine.anatomical_structure
Fibrosis
Chronic Conjunctivitis
medicine
Humans
Surgery
Stage (cooking)
business
Direct fluorescent antibody
Subjects
Details
- ISSN :
- 15372677
- Volume :
- 37
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Ophthalmic plastic and reconstructive surgery
- Accession number :
- edsair.doi.dedup.....34becc6936e1eb075daa9d8c46e8e8cb