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Normocalcemic Hyperparathyroidism
- Source :
- Archives of Surgery. 127:1157
- Publication Year :
- 1992
- Publisher :
- American Medical Association (AMA), 1992.
-
Abstract
- • Patients with normocalcemic hyperparathyroidism represent a diagnostic and therapeutic challenge. It is unclear to what extent these patients benefit from surgery in terms of correction of their serum chemistry abnormalities and their symptoms. We studied 142 patients: 23 with normocalcemic hyperparathyroidism (serum calcium levels below 2.62 mmol/L), 35 with intermittent hypercalcemia, and 84 with hypercalcemic hyperparathyroidism. Serum chemistry analyses and a standardized questionnaire of symptoms were completed before and after surgery. Overall, patients in the normocalcemic group reported a similar frequency of preoperative symptoms; had a similar reduction in postoperative symptoms; and had a similar normalization of serum calcium, parathormone, and phosphate levels as those in the two control groups. This study indicates that factors other than elevated serum calcium levels are in large part responsible for the symptoms of hyperparathyroidism and that these patients benefit from operation. (Arch Surg.1992;127:1157-1163)
- Subjects :
- Adenoma
Adult
Male
medicine.medical_specialty
Adolescent
endocrine system diseases
chemistry.chemical_element
Calcium
Neoplasms, Multiple Primary
Parathyroid Glands
Clinical investigation
medicine
Humans
Aged
Aged, 80 and over
Parathyroidectomy
Hyperparathyroidism
Hyperplasia
business.industry
Middle Aged
medicine.disease
Surgery
Elevated serum calcium
Parathyroid Neoplasms
Symptom profiles
chemistry
Parathyroid Hormone
Hypercalcemia
Female
business
Serum chemistry
Subjects
Details
- ISSN :
- 00040010
- Volume :
- 127
- Database :
- OpenAIRE
- Journal :
- Archives of Surgery
- Accession number :
- edsair.doi.dedup.....34e10d6cc30cf2530b1bd920af6759da