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Endoscopic findings in patients with familial Mediterranean fever and dyspeptic symptoms
- Source :
- Przegla̜d Gastroenterologiczny, Gastroenterology Review, Vol 13, Iss 3, Pp 238-241 (2018)
- Publication Year :
- 2018
- Publisher :
- Termedia Publishing House, 2018.
-
Abstract
- Aim: The aim of the study was to evaluate the clinical, endoscopic, histopathological, laboratory, and imaging findings of patients with familial Mediterranean fever (FMF) presenting with dyspeptic symptoms. Material and methods: Endoscopy was performed in 28 patients with FMF undergoing colchicine therapy, who presented to our hospital between 2012 and 2014 with abdominal pain, diarrhoea, and dyspeptic complaints. Upper gastrointestinal system endoscopy was performed in all patients; 16 of these underwent colonoscopy. Demographic characteristics, clinical and laboratory data, genetic analysis, imaging data, and endoscopy and colonoscopy findings were evaluated in all patients. Results: Histopathological analysis of biopsy specimens revealed gastrointestinal pathology in 21 (75%) patients. Upper endoscopy analysis revealed that 14 (50%) patients had antral gastritis (8 Helicobacter pylori (-) antral gastritis and 6 H. pylori (+) chronic active gastritis) and 2 (7%) cases had giardiasis. Four antral gastritis cases had concomitant esophagitis, and 2 patients had widespread ulcers in the terminal ileum. The rest had a normal colonic appearance; however, three patients with normal colonoscopic findings were found to have chronic active colitis on histopathological examination. Conclusions: In this study, most patients with FMF presenting with dyspeptic complaints had gastrointestinal pathology. Furthermore, there was higher inflammatory bowel disease incidence in these patients. © 2018 Termedia Publishing House Ltd. All rights reserved.
- Subjects :
- medicine.medical_specialty
Abdominal pain
MEFV
Colonoscopy
Familial Mediterranean fever
lcsh:Medicine
dyspepsia
Gastroenterology
Inflammatory bowel disease
03 medical and health sciences
0302 clinical medicine
familial Mediterranean fever
inflammatory bowel disease
Internal medicine
medicine
endoscopy
Original Paper
medicine.diagnostic_test
biology
business.industry
lcsh:R
Gastrointestinal pathology
Helicobacter pylori
biology.organism_classification
medicine.disease
030220 oncology & carcinogenesis
030211 gastroenterology & hepatology
Gastritis
medicine.symptom
business
Esophagitis
Subjects
Details
- Language :
- English
- ISSN :
- 18974317 and 18955770
- Volume :
- 13
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Przegla̜d Gastroenterologiczny
- Accession number :
- edsair.doi.dedup.....3591986c3e76b67fd3689f85b05ed80b