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Long-term efficacy of partial splenic embolization in children
- Source :
- Journal of Pediatric Surgery. 38:1760-1762
- Publication Year :
- 2003
- Publisher :
- Elsevier BV, 2003.
-
Abstract
- Purpose: To elucidate the role of partial splenic embolization (PSE) procedures, long-term outcome was assessed in terms of the recurrence of thrombocytopenia. Methods: A retrospective study was performed after 41 PSE procedures in 36 patients for hypersplenism owing to portal hypertension. The underlying disease was biliary atresia in 32 patients, extrahepatic portal obstruction in 3, and idiopathic cirrhosis in 1. Results: The average volume embolized was 70.1%. The patients were followed up from 20 days to 182 months (average, 70.8 months). Five patients subsequently died, and 6 underwent liver transplantation. The causes of death or the reasons for liver transplantation were not related to hypersplenism. Eleven patients (30.6%) had recurrence of thrombocytopenia ( 3 ). There was no significant difference in the volume embolized or platelet count before PSE between the patients with and without recurrence of thrombocytopenia. The peak value of platelet count after PSE was significantly lower in the patients with recurrence of thrombocytopenia ( P = .0091). In 17 of 24 survivors without liver transplantation, platelet counts remained normal throughout the follow-up period. Conclusions: PSE is a safe and effective procedure. Hematologic indices improved in all 36 patients after PSE, and its long-term efficacy was shown in 70% of the survivors.
- Subjects :
- Liver Cirrhosis
Male
medicine.medical_specialty
Cirrhosis
Adolescent
medicine.medical_treatment
Liver transplantation
Hypersplenism
Cholestasis
Biliary Atresia
Recurrence
Biliary atresia
Hypertension, Portal
medicine
Humans
Platelet
Embolization
Child
Retrospective Studies
business.industry
Infant
Retrospective cohort study
General Medicine
Cholestasis, Extrahepatic
medicine.disease
Embolization, Therapeutic
Thrombocytopenia
Liver Transplantation
Surgery
Child, Preschool
Pediatrics, Perinatology and Child Health
Portal hypertension
Female
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 00223468
- Volume :
- 38
- Database :
- OpenAIRE
- Journal :
- Journal of Pediatric Surgery
- Accession number :
- edsair.doi.dedup.....3697d7d76f9c949bcb63882275fbc631