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Additional file 5 of CDK4/6 inhibitors sensitize gammaherpesvirus-infected tumor cells to T-cell killing by enhancing expression of immune surface molecules

Authors :
Wu, Yiquan
Shrestha, Prabha
Heape, Natalie M.
Yarchoan, Robert
Publication Year :
2022
Publisher :
figshare, 2022.

Abstract

Additional file 5. Abe increases cell surface expression of ICAM-1, B7-2, and PD-L1 in PEL cell lines and EBV-infected BL cell lines. JSC-1 (a), BCBL-1 (b), Akata (c), and Raji (d) cells were treated with abemaciclib, or with RPMI medium control for 3 days. Surface expression of ICAM-1, B7-2 and PD-L1 were analyzed by flow cytometry. Results shown are one representative experiment of 3 separate experiments.

Subjects

Subjects :
hemic and lymphatic diseases

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....369e64e1b097bbfacbc7401b61fc6901
Full Text :
https://doi.org/10.6084/m9.figshare.19766322