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Wild-Type and Genetically Improved Strains of Dairy Origin Probiotic as Potential Treatments for Intestinal Mucositis
- Source :
- Journal of Pharmacy and Pharmacology, Journal of Pharmacy and Pharmacology, Royal Pharmaceutical Society of Great Britain, 2019, 7, pp.177-186, Journal of Pharmacy and Pharmacology, Royal Pharmaceutical Society of Great Britain, 2019, 7, pp.177-186. ⟨10.17265/2328-2150/2019.04.004⟩
- Publication Year :
- 2019
- Publisher :
- David Publishing Company, 2019.
-
Abstract
- The use of probiotic bacteria derived from fermented foods has been explored by the scientific community as alternative strategies for the treatment of several diseases, mainly regarding intestinal dysfunction. One of the most relevant inflammatory diseases affecting the alimentary tract, for which no current intervention is entirely successful, is mucositis. In this review article, we summarize the most recent proof-of-concept studies dealing with the therapeutic use of dairy origin probiotics, for the treatment of gastrointestinal mucositis. Furthermore, we discuss several approaches for the improvement of the classical therapeutic rationale, such as supplementation with prebiotics and genetic engineering along with the respective translational issues, which may be crucial for the successful transposition of these therapeutic strategies for clinical use.
- Subjects :
- prebiotique
Biology
human health
allégations nutritionnelles et de santé
produit laitier
Microbiology
law.invention
pharmacotherapy
03 medical and health sciences
Probiotic
0302 clinical medicine
intestin
law
[SDV.IDA]Life Sciences [q-bio]/Food engineering
chimiothérapie
Mucositis
medicine
inflammation gastrointestinale
030304 developmental biology
0303 health sciences
Wild type
santé humaine
probiotique
medicine.disease
3. Good health
[SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology
dairy product
030220 oncology & carcinogenesis
inflammation du tube digestif
[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
probiotic
Subjects
Details
- ISSN :
- 23282150 and 00223573
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- Journal of Pharmacy and Pharmacology
- Accession number :
- edsair.doi.dedup.....36b0bf8ca1686a7c82af20d89aa826a7