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Treatment of -En Coup de Sabre- Deformity With Adipose-Derived Regenerative Cell-Enriched Fat Graft
- Publication Year :
- 2012
-
Abstract
- Linear scleroderma "en coup de sabre" is characterized by atrophy and furrowing of the skin of the front parietal region above the level of the eyebrow. In most cases, it occurs as a single paramedian line that may be associated with hypoplasia of underlying structures and hemiatrophy of the face. The affected region is a depression that may be associated with hypoplasia of the underlying soft tissues and bone that results in facial hemiatrophy. If the lesion is narrow, it can be resected and directly sutured; in the case of a wide lesion, many different reconstructive techniques, directed at augmentation of deficient soft tissue volume, have been proposed such as autologous tissue grafts, biomaterials, pedicled flaps, and free flaps. Adipose-derived regenerative cells (ADRCs) can be easily processed from lipoaspirated fat and can provide a significant quantity of multipotent cells for a variety of therapeutic regenerative medicine therapies. There is an increasing interest in a possible therapeutic role of ADRCs from processed lipoaspirate for many applications, including their use as soft-tissue fillers. We introduce the application of a successful ADRC therapy for a linear scleroderma en coup de sabre deformity.
- Subjects :
- medicine.medical_specialty
Subcutaneous Fat
Adipose tissue
Regenerative medicine
Scleroderma, Localized
Young Adult
medicine
Deformity
Hemiatrophy
Adipocytes
Humans
Linear Scleroderma
Forehead
Karaaltin M. V. , Akpinar A. C. , Baghaki S., Akpinar F., -Treatment of -En Coup de Sabre- Deformity With Adipose-Derived Regenerative Cell-Enriched Fat Graft-, JOURNAL OF CRANIOFACIAL SURGERY, cilt.23, 2012
business.industry
Soft tissue
General Medicine
Pedicled Flap
medicine.disease
Hypoplasia
Surgery
Otorhinolaryngology
Female
medicine.symptom
business
Stem Cell Transplantation
Subjects
Details
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....379747261d86679047e9e9b47357b993