What about the role of cryoablation for isolation of non-pulmonary vein triggers in long-standing persistent atrial fibrillation?

In their recent case report, Aksu et al.[1] demonstrated additional features of cryoballoon ablation aside from pulmonary vein isolation (PVI) in a patient with longstanding persistent atrial fibrillation (LPAF). Confirmatory to previous studies, they presented a reduction in both antral and posterior complex fractionated atrial electrogram (CFAE) areas just after PVI with cryoballoon-based therapy. They also performed additional ablation for other CFAE areas at anterior left atrium with radiofrequency (RF) energy.