Back to Search
Start Over
Membranous Nephropathy in Children
- Source :
- Pediatric Nephrology ISBN: 9783662435953, Pediatric Nephrology ISBN: 9783642278433
- Publication Year :
- 2015
- Publisher :
- Springer Berlin Heidelberg, 2015.
-
Abstract
- Membranous nephropathy (MN), also known as membranous glomerulonephritis, is a pathologic condition associated with an immune complex deposition within the glomerulus resulting in glomerular dysfunction. Clinical manifestations of MN include proteinuria, hematuria, overt nephrotic syndrome, and in some cases renal dysfunction. In adults, MN is the most common primary glomerulopathy associated with the nephrotic syndrome, accounting for approximately 25–35% of adults diagnosed with this condition [1–3]. In children, MNmay present as the nephrotic syndrome or as asymptomatic proteinuria and is considered to a much less common condition than that seen in adults [4, 5]. MNmay be idiopathic or secondary to infections, autoimmune diseases, or medications. Recent breakthrough discoveries regarding the pathogenesis of idiopathic MN have reenergized the field and should aid clinicians going forward with regard to developing novel means to monitor and treat patients with membranous nephropathy [6–8].
- Subjects :
- medicine.medical_specialty
Proteinuria
business.industry
Glomerulonephritis
urologic and male genital diseases
medicine.disease
Gastroenterology
Pathogenesis
Membranous nephropathy
Glomerulopathy
Internal medicine
Asymptomatic proteinuria
Immune complex deposition
medicine
medicine.symptom
business
Nephrotic syndrome
Subjects
Details
- ISBN :
- 978-3-662-43595-3
978-3-642-27843-3 - ISBNs :
- 9783662435953 and 9783642278433
- Database :
- OpenAIRE
- Journal :
- Pediatric Nephrology ISBN: 9783662435953, Pediatric Nephrology ISBN: 9783642278433
- Accession number :
- edsair.doi.dedup.....37f80f17c938c26b6b3d70d71ade4f8e