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Dysfunction of rapid neural adaptation in dyslexia
- Source :
- PMC
- Publication Year :
- 2016
-
Abstract
- Identification of specific neurophysiological dysfunctions resulting in selective reading difficulty (dyslexia) has remained elusive. In addition to impaired reading development, individuals with dyslexia frequently exhibit behavioral deficits in perceptual adaptation. Here, we assessed neurophysiological adaptation to stimulus repetition in adults and children with dyslexia for a wide variety of stimuli, spoken words, written words, visual objects, and faces. For every stimulus type, individuals with dyslexia exhibited significantly diminished neural adaptation compared to controls in stimulus-specific cortical areas. Better reading skills in adults and children with dyslexia were associated with greater repetition-induced neural adaptation. These results highlight a dysfunction of rapid neural adaptation as a core neurophysiological difference in dyslexia that may underlie impaired reading development. Reduced neurophysiological adaptation may relate to prior reports of reduced behavioral adaptation in dyslexia and may reveal a difference in brain functions that ultimately results in a specific reading impairment.<br />NIH (Grant UL1RR025758)
- Subjects :
- Adult
Male
medicine.medical_specialty
Speech perception
Audiology
Stimulus (physiology)
Biological theories of dyslexia
behavioral disciplines and activities
050105 experimental psychology
Article
Dyslexia
03 medical and health sciences
Young Adult
0302 clinical medicine
Neuroimaging
Functional neuroimaging
Phonetics
mental disorders
medicine
Humans
0501 psychology and cognitive sciences
General Neuroscience
Functional Neuroimaging
05 social sciences
Neural adaptation
Brain
medicine.disease
Adaptation, Physiological
Magnetic Resonance Imaging
nervous system diseases
Developmental disorder
medicine.anatomical_structure
Memory, Short-Term
Case-Control Studies
Auditory Perception
Speech Perception
Female
Psychology
030217 neurology & neurosurgery
Cognitive psychology
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- PMC
- Accession number :
- edsair.doi.dedup.....3867eea48c01689acc04741817f76dfe