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Prolactin-releasing peptide increases food intake and affects hypothalamic physiology in Japanese quail (Coturnix japonica)
Prolactin-releasing peptide increases food intake and affects hypothalamic physiology in Japanese quail (Coturnix japonica)
- Source :
- Domestic Animal Endocrinology. 72:106464
- Publication Year :
- 2020
- Publisher :
- Elsevier BV, 2020.
-
Abstract
- Prolactin-releasing peptide (PrRP) increases food intake in birds, whereas it is a potent satiety factor in rodents and fish. The aim of this study was to determine the effects of central injection of PrRP on feeding behaviors and hypothalamic physiology in juvenile Japanese quail (Coturnix japonica). Intracerebroventricular injection of 1,692 pmol of PrRP increased food intake for the first 90 min after injection but did not affect water intake. Quail treated with PrRP displayed more food and drink pecks, less time standing but more perching, and decreased defecations. Prolactin-releasing peptide–injected quail had increased c-Fos immunoreactivity in the dorsomedial nucleus (DMN) and arcuate nucleus (ARC) of the hypothalamus. Hypothalamic neuropeptide Y receptor subtypes 2 and 5 and melanocortin receptor 4 mRNAs were greater in PrRP- than vehicle-injected quail. In the DMN, there was less corticotropin-releasing factor (CRF) mRNA and in the ARC, more CRF mRNA in PrRP- than vehicle-injected chicks. Thus, PrRP increases food intake in quail, which is associated with changes in hypothalamic CRF and neuropeptide Y receptor gene expression and c-Fos-immunolabeled cells in the ARC and DMN.
- Subjects :
- Male
medicine.medical_specialty
Corticotropin-Releasing Hormone
Prolactin-releasing peptide
media_common.quotation_subject
Hypothalamus
Physiology
Coturnix
Biology
Endocrinology
Food Animals
biology.animal
Internal medicine
medicine
Animals
RNA, Messenger
media_common
Prolactin-Releasing Hormone
Arc (protein)
Behavior, Animal
Coturnix japonica
Appetite
Feeding Behavior
Neuropeptide Y receptor
biology.organism_classification
Quail
Melanocortin 4 receptor
Infusions, Intraventricular
Gene Expression Regulation
Female
Animal Science and Zoology
Proto-Oncogene Proteins c-fos
hormones, hormone substitutes, and hormone antagonists
Subjects
Details
- ISSN :
- 07397240
- Volume :
- 72
- Database :
- OpenAIRE
- Journal :
- Domestic Animal Endocrinology
- Accession number :
- edsair.doi.dedup.....38eefbca15416136e6153754efd2184d
- Full Text :
- https://doi.org/10.1016/j.domaniend.2020.106464