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Pulmonary Aspergillosis: Spectrum of Disease
- Source :
- The American Journal of the Medical Sciences. 361:411-419
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Aspergillus species are ubiquitous in the environment. Aspergillosis is acquired by inhalation of Aspergillus spores. In normal hosts, spore inhalation rarely causes lung disease. Pulmonary Aspergillosis covers a wide spectrum of clinical syndromes depending on the interaction between Aspergillus and the host (immune-status, prior bronchopulmonary disease). It runs the gamut from invasive Aspergillosis to Aspergillus bronchitis. Invasive Aspergillosis usually occurs in severely immunocompromised patients, typically in neutropenic but also in non-neutropenic patients. Chronic pulmonary Aspergillosis affects patients with chronic structural lung disease such as COPD or previous mycobacterial lung disease, but without other significant immunocompromise. Aspergillus bronchitis affects patients with bronchial disease such as bronchiectasis. Allergic bronchopulmonary Aspergillosis affects patients with bronchial asthma or cystic fibrosis, and is due to an allergic response to Aspergillus.
- Subjects :
- Aspergillus
COPD
Bronchiectasis
biology
business.industry
Chronic pulmonary aspergillosis
General Medicine
030204 cardiovascular system & hematology
medicine.disease
biology.organism_classification
Aspergillosis
Cystic fibrosis
respiratory tract diseases
03 medical and health sciences
0302 clinical medicine
Immunology
medicine
Humans
Pulmonary Aspergillosis
030212 general & internal medicine
Allergic bronchopulmonary aspergillosis
business
Asthma
Subjects
Details
- ISSN :
- 00029629
- Volume :
- 361
- Database :
- OpenAIRE
- Journal :
- The American Journal of the Medical Sciences
- Accession number :
- edsair.doi.dedup.....39356e8daec87aa6604de72fe22a44a8