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Multidimensional assessment of voice characteristics after radiotherapy for early glottic cancer
- Source :
- Verdonck-De Leeuw, I M, Hilgers, F J M, Keus, R B, Koopmans-Van Beinum, F J, Greven, J, De Jong, J M A, Vreeburg, G & Bartelink, H 1999, ' Multidimensional assessment of voice characteristics after radiotherapy for early glottic cancer ', Laryngoscope, vol. 109, no. 2, pp. 241-248 . https://doi.org/10.1097/00005537-199902000-00014, The Laryngoscope, 109, 241-248. Wiley-Blackwell, Laryngoscope, 109(2), 241-248. Wiley-Blackwell
- Publication Year :
- 2000
-
Abstract
- Objectives/Hypothesis: To assess voice characteristics of patients following radiotherapy for early glottic cancer through a multidimensional analysis protocol including vocal function and voice quality measures. Methods: Voice analyses were performed for 60 patients treated with radiotherapy (66 Gy/33 fractions, 60 Gy/30 fractions, or 60 Gy/25 fractions) for early T1 glottic cancer and 20 matched control speakers. There was a longitudinal group of 10 patients for whom data were collected before as well as 6 months and 2 years after radiation. Furthermore, data were collected for five separate groups of 10 patients each, before, 6 months after, 2 years after, 3 to 7 years after, and 7 to 10 years after radiation. Vocal function was investigated by means of videolaryngostroboscopy, phonetography, maximum phonation time, and phonation quotient measures. Voice quality was assessed by means of objective acoustical analysis and subjective perceptual ratings by trained raters. Results: Voice characteristics of patients were decreased before radiotherapy, improved after treatment, and became comparable to the voice characteristics of control speakers in at least 55% of the patients. Following radiotherapy, deviant voice quality was mainly negatively affected by increased age and stripping the vocal cord for initial diagnosis. Stroboscopy revealed that next to increasing age and stripping the vocal cord, continued smoking after treatment decreased vocal function following radio-therapy. Conclusion: Voices of patients diagnosed with early glottic cancer improved but did not normalize fully after radiotherapy. Stripping the vocal cord for initial diagnosis and continued smoking after treatment decreased voice characteristics. A multidimensional analysis protocol including perceptual and acoustical analysis of voice quality and stroboscopic analysis of vocal function is recommended to investigate voice characteristics following treatment for early glottic cancer.
- Subjects :
- Phonation quotient
medicine.medical_specialty
Glottis
Cord
Time Factors
Voice Quality
medicine.medical_treatment
Multidimensional assessment
Audiology
Severity of Illness Index
Stroboscope
Speech Production Measurement
Phonetics
medicine
otorhinolaryngologic diseases
Humans
Prospective Studies
Laryngeal Neoplasms
Aged
Neoplasm Staging
Voice Disorders
business.industry
Carcinoma
Smoking
Maximum phonation time
Age Factors
Dose-Response Relationship, Radiation
Middle Aged
Surgery
Radiation therapy
medicine.anatomical_structure
Otorhinolaryngology
Glottic cancer
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 0023852X
- Volume :
- 109
- Issue :
- 2 Pt 1
- Database :
- OpenAIRE
- Journal :
- The Laryngoscope
- Accession number :
- edsair.doi.dedup.....39ddf8873ecb33750d494916eea48655