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From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on 'New frontiers in cardiovascular research'
- Source :
- SCOPUS03008428-2016-111-6-SID84991383711, Basic Research in Cardiology, Basic Res Cardiol 111(6), 69 (2016). doi:10.1007/s00395-016-0586-x, Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid, Consejería de Sanidad de la Comunidad de Madrid, Cabrera-Fuentes, H A, Aragones, J, Bernhagen, J, Boening, A, Boisvert, W A, Bøtker, H E, Bulluck, H, Cook, S, Di Lisa, F, Engel, F B, Engelmann, B, Ferrazzi, F, Ferdinandy, P, Fong, A, Fleming, I, Gnaiger, E, Hernández-Reséndiz, S, Kalkhoran, S B, Kim, M H, Lecour, S, Liehn, E A, Marber, M S, Mayr, M, Miura, T, Ong, S-B, Peter, K, Sedding, D, Singh, M K, Suleiman, M S, Schnittler, H J, Schulz, R, Shim, W, Tello, D, Vogel, C-W, Walker, M, Li, Q O Y, Yellon, D M, Hausenloy, D J & Preissner, K T 2016, ' From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics : meeting report from the third international symposium on "New frontiers in cardiovascular research" ', Basic Research in Cardiology, vol. 111, no. 6, pp. 69 . https://doi.org/10.1007/s00395-016-0586-x, Cabrera-Fuentes, H A, Aragones, J, Bernhagen, J, Boening, A, Boisvert, W A, Bøtker, H E, Bulluck, H, Cook, S, Di Lisa, F, Engel, F B, Engelmann, B, Ferrazzi, F, Ferdinandy, P, Fong, A, Fleming, I, Gnaiger, E, Hernández-Reséndiz, S, Kalkhoran, S B, Kim, M H, Lecour, S, Liehn, E A, Marber, M S, Mayr, M, Miura, T, Ong, S-B, Peter, K, Sedding, D, Singh, M K, Suleiman, M S, Schnittler, H J, Schulz, R, Shim, W, Tello, D, Vogel, C-W, Walker, M, Li, Q O Y, Yellon, D M, Hausenloy, D J & Preissner, K T 2016, ' From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics : meeting report from the third international symposium on "New frontiers in cardiovascular research" ', Basic Research in Cardiology, vol. 111, no. 6, pp. 69-81 . https://doi.org/10.1007/s00395-016-0586-x, Cabrera-Fuentes, H A, Aragones, J, Bernhagen, J, Boening, A, Boisvert, W A, Bøtker, H E, Bulluck, H, Cook, S, Di Lisa, F, Engel, F B, Engelmann, B, Ferrazzi, F, Ferdinandy, P, Fong, A, Fleming, I, Gnaiger, E, Hernández-Reséndiz, S, Kalkhoran, S B, Kim, M H, Lecour, S, Liehn, E A, Marber, M, Mayr, M, Miura, T, Ong, S B, Peter, K, Sedding, D, Singh, M K, Suleiman, M S, Schnittler, H J, Schulz, R, Shim, W, Tello, D, Vogel, C W, Walker, M, Li, Q O Y, Yellon, D M, Hausenloy, D J & Preissner, K T 2016, ' From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics : meeting report from the third international symposium on “New frontiers in cardiovascular research” ', Basic Research in Cardiology, vol. 111, no. 6, 69 . https://doi.org/10.1007/s00395-016-0586-x
- Publication Year :
- 2016
-
Abstract
- In this meeting report, particularly addressing the topic of protection of the cardiovascular system from ischemia/reperfusion injury, highlights are presented that relate to conditioning strategies of the heart with respect to molecular mechanisms and outcome in patients’ cohorts, the influence of co-morbidities and medications, as well as the contribution of innate immune reactions in cardioprotection. Moreover, developmental or systems biology approaches bear great potential in systematically uncovering unexpected components involved in ischemia–reperfusion injury or heart regeneration. Based on the characterization of particular platelet integrins, mitochondrial redox-linked proteins, or lipid-diol compounds in cardiovascular diseases, their targeting by newly developed theranostics and technologies opens new avenues for diagnosis and therapy of myocardial infarction to improve the patients’ outcome. © 2016, The Author(s).
- Subjects :
- Drug targeting
Cardiomyocyte signaling pathways
Cardioprotection
Cardiovascular disease
Co-morbidities
Endothelial permeability
Extracellular RNA (eRNA)
Heart regeneration
Induced pluripotent stem cells
Ischemia–reperfusion injury
Lipid metabolism
MicroRNAs (miRNAs)
Mitochondria
Remote ischemic conditioning
Animals
Cardiology
Humans
Theranostic Nanomedicine
Cardiovascular Diseases
Review
reactive oxygen metabolite
Meeting Report
atherectomy
Comorbidities
sepsis
0302 clinical medicine
toll like receptor 4
high density lipoprotein cholesterol
Myocardial infarction
cardiac muscle cell
disease course
pilot study
immunosuppressive treatment
pancreatic ribonuclease
cohort analysis
3. Good health
Cardiology and Cardiovascular Medicine
drug eluting stent
signal transduction
medicine.medical_specialty
Extracellular RNA (eRNA) H
immunothrombosis
Ischemia
insulin dependent diabetes mellitus
Heart protection
in vivo study
03 medical and health sciences
coronary artery bypass graft
vascular endothelial cadherin
Physiology (medical)
human
procedures
Intensive care medicine
protein expression
ST segment elevation myocardial infarction
percutaneous coronary intervention
medicine.disease
heart surgery
protein phosphorylation
macrophage migration inhibition factor
030104 developmental biology
Immunology
hemolytic uremic syndrome
atherosclerosis
0301 basic medicine
Physiology
030204 cardiovascular system & hematology
heart mitochondrion
heart infarction size
high mobility group B1 protein
oxidative stress
animal
randomized controlled trial (topic)
innate immunity
troponin T
disseminated intravascular clotting
atherogenesis
unclassified drug
comorbidity
multicenter study (topic)
trends
tumor necrosis factor
Systems biology
Cardiovascular research
1102 Cardiovascular Medicine And Haematology
heart protection
cardiovascular magnetic resonance
STAT3 protein
retinopathy
troponin I
Escherichia coli
medicine
In patient
ddc:610
thrombosis
nonhuman
business.industry
disease association
non ST segment elevation myocardial infarction
myocardial ischemia reperfusion injury
7 INGENIERÍA Y TECNOLOGÍA
Cardiovascular System & Hematology
macrophage migration inhibition factor 2
protein kinase B
business
Reperfusion injury
chronic kidney disease
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- SCOPUS03008428-2016-111-6-SID84991383711, Basic Research in Cardiology, Basic Res Cardiol 111(6), 69 (2016). doi:10.1007/s00395-016-0586-x, Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid, Consejería de Sanidad de la Comunidad de Madrid, Cabrera-Fuentes, H A, Aragones, J, Bernhagen, J, Boening, A, Boisvert, W A, Bøtker, H E, Bulluck, H, Cook, S, Di Lisa, F, Engel, F B, Engelmann, B, Ferrazzi, F, Ferdinandy, P, Fong, A, Fleming, I, Gnaiger, E, Hernández-Reséndiz, S, Kalkhoran, S B, Kim, M H, Lecour, S, Liehn, E A, Marber, M S, Mayr, M, Miura, T, Ong, S-B, Peter, K, Sedding, D, Singh, M K, Suleiman, M S, Schnittler, H J, Schulz, R, Shim, W, Tello, D, Vogel, C-W, Walker, M, Li, Q O Y, Yellon, D M, Hausenloy, D J & Preissner, K T 2016, ' From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics : meeting report from the third international symposium on "New frontiers in cardiovascular research" ', Basic Research in Cardiology, vol. 111, no. 6, pp. 69 . https://doi.org/10.1007/s00395-016-0586-x, Cabrera-Fuentes, H A, Aragones, J, Bernhagen, J, Boening, A, Boisvert, W A, Bøtker, H E, Bulluck, H, Cook, S, Di Lisa, F, Engel, F B, Engelmann, B, Ferrazzi, F, Ferdinandy, P, Fong, A, Fleming, I, Gnaiger, E, Hernández-Reséndiz, S, Kalkhoran, S B, Kim, M H, Lecour, S, Liehn, E A, Marber, M S, Mayr, M, Miura, T, Ong, S-B, Peter, K, Sedding, D, Singh, M K, Suleiman, M S, Schnittler, H J, Schulz, R, Shim, W, Tello, D, Vogel, C-W, Walker, M, Li, Q O Y, Yellon, D M, Hausenloy, D J & Preissner, K T 2016, ' From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics : meeting report from the third international symposium on "New frontiers in cardiovascular research" ', Basic Research in Cardiology, vol. 111, no. 6, pp. 69-81 . https://doi.org/10.1007/s00395-016-0586-x, Cabrera-Fuentes, H A, Aragones, J, Bernhagen, J, Boening, A, Boisvert, W A, Bøtker, H E, Bulluck, H, Cook, S, Di Lisa, F, Engel, F B, Engelmann, B, Ferrazzi, F, Ferdinandy, P, Fong, A, Fleming, I, Gnaiger, E, Hernández-Reséndiz, S, Kalkhoran, S B, Kim, M H, Lecour, S, Liehn, E A, Marber, M, Mayr, M, Miura, T, Ong, S B, Peter, K, Sedding, D, Singh, M K, Suleiman, M S, Schnittler, H J, Schulz, R, Shim, W, Tello, D, Vogel, C W, Walker, M, Li, Q O Y, Yellon, D M, Hausenloy, D J & Preissner, K T 2016, ' From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics : meeting report from the third international symposium on “New frontiers in cardiovascular research” ', Basic Research in Cardiology, vol. 111, no. 6, 69 . https://doi.org/10.1007/s00395-016-0586-x
- Accession number :
- edsair.doi.dedup.....39fade24bc6f504c4b327053146f9081