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Pulmonary Iron Overload in Thalassemia major Presenting as Small Airway Disease
- Source :
- Acta Haematologica. 108:43-46
- Publication Year :
- 2002
- Publisher :
- S. Karger AG, 2002.
-
Abstract
- Lung function abnormalities that are associated with thalassemia major are variable with etiology that is yet undetermined. Some studies have suggested that pulmonary iron deposition is a probable cause for these lung defects although there has been no antemortem histopathological and radiological evidence for this. We report a case of thalassemia major with biopsy-proven pulmonary iron overload, in which thoracic high-resolution computed tomography revealed a morphological-functional correlation consistent with small airway disease.
- Subjects :
- Adult
Lung Diseases
Hemolytic anemia
Pathology
medicine.medical_specialty
Iron Overload
Biopsy
medicine.medical_treatment
Thalassemia
Splenectomy
Hemosiderin
Deferoxamine
Iron Chelating Agents
Hypothyroidism
medicine
Humans
Insulin
Lung
business.industry
Macrophages
beta-Thalassemia
Respiratory disease
Transfusion Reaction
Hematology
General Medicine
medicine.disease
Combined Modality Therapy
Chelation Therapy
Airway Obstruction
Diabetes Mellitus, Type 1
medicine.anatomical_structure
Hemoglobinopathy
Etiology
Patient Compliance
Female
Kidney Diseases
Tomography, X-Ray Computed
business
Complication
Subjects
Details
- ISSN :
- 14219662 and 00015792
- Volume :
- 108
- Database :
- OpenAIRE
- Journal :
- Acta Haematologica
- Accession number :
- edsair.doi.dedup.....3a0f539ddee67ec260a19328d348a9df