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<scp>Clin‐Star</scp> corner: What's new at the interface of geriatrics, infectious diseases, and antimicrobial stewardship

Authors :
Sonali D. Advani
Kenneth E. Schmader
Lona Mody
Source :
Journal of the American Geriatrics Society. 70:2214-2218
Publication Year :
2022
Publisher :
Wiley, 2022.

Abstract

Antibiotics are among the leading causes of adverse drug events in older adults. Short-course antibiotic therapy has been shown to work as well as the traditional longer durations for many types of infections. Antibiotic stewardship interventions including deprescribing strategies have shown a reduction in patient readmissions and mortality among older adults. We identified practice-changing clinical trials focusing on three major domains of overprescribing antibiotics in older adults - community-acquired pneumonia, urinary tract infections, and gram-negative bacteremia. The selected articles underscore the safety and effectiveness of shorter durations of antibiotic treatment for infections in older adults, thus highlighting an opportunity for deprescribing in the aging population. By optimizing antibiotic use, we stand to reduce adverse events and enhance overall health outcomes in older adults.

Details

ISSN :
15325415 and 00028614
Volume :
70
Database :
OpenAIRE
Journal :
Journal of the American Geriatrics Society
Accession number :
edsair.doi.dedup.....3a17747629b71bb08a68d0cdd9306ed3
Full Text :
https://doi.org/10.1111/jgs.17907