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Assessment of a downsized potassium adsorption filter designed to transfuse neonates
- Source :
- Transfusion. 60:2494-2499
- Publication Year :
- 2020
- Publisher :
- Wiley, 2020.
-
Abstract
- Background During storage, the potassium level of red blood cell (RBC) components increases, especially after irradiation. Neonates are prone to hyperkalemia, for example, non-oliguric hyperkalemia, so using potassium adsorption filters during transfusion may be helpful. To overcome dilution of RBC components caused by saline priming of existing potassium adsorption filters, a downsized potassium adsorption filter for neonates (PAF-n, Kawasumi Laboratories Inc., Tokyo, Japan) was developed. Study design and methods To assess the performance of PAF-n, its adsorption efficiency and RBC recovery rate were evaluated by testing pre-filtration and serial post-filtration (0-30 mL, 30-60 mL, 60-90 mL, and 90-120 mL) samples from 8 RBC components. Results The average potassium adsorption rate of the PAF-n was 90.5% ± 0.78%, and never less than 89.0% in any of 8 RBC components. RBC recovery rates were 99.3% ± 1.12%. Conclusion The PAF-n showed an effective potassium ability with negligible RBC dilution.
- Subjects :
- Hyperkalemia
Potassium
medicine.medical_treatment
Immunology
chemistry.chemical_element
030204 cardiovascular system & hematology
03 medical and health sciences
0302 clinical medicine
Adsorption
Recovery rate
medicine
Humans
Immunology and Allergy
Saline
Chromatography
Infant, Newborn
Hematology
Dilution
Red blood cell
medicine.anatomical_structure
chemistry
medicine.symptom
Erythrocyte Transfusion
Potassium level
030215 immunology
Subjects
Details
- ISSN :
- 15372995 and 00411132
- Volume :
- 60
- Database :
- OpenAIRE
- Journal :
- Transfusion
- Accession number :
- edsair.doi.dedup.....3a3a803e1e7b7315d0a991096d16b13f